DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31780 and proca

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_956650.1	Gene:	proca / 393327	ZFINID:	ZDB-GENE-060824-5	Length:	434	Species:	Danio rerio

Alignment Length:	355	Identity:	91/355 - (25%)
Similarity:	158/355 - (44%)	Gaps:	78/355 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 QGQNAELNQ---SCGASN---EHQCVPRHMCKVKIEFRMAMTYRNLGCV-------STAICCPKN 74
            :|::.:|.:   :|..:|   :|.|   |..|..:.       |...|:       ::..|.|||
Zfish   115 EGKHCDLRRTATNCSLNNGDCDHDC---HESKDGLA-------RTCSCIKGYQLQDNSRKCTPKN 169

  Fly    75 LIIKEPRLIINEPITDPQCGFVNSKGVTFSFREEDT--------GLAQEAEVPWMVALLDARTSS 131
                           |..||.:......::.:.:..        .:.:..|.||...:|: ....
Zfish   170 ---------------DASCGQIRIPKSAYANKPKPVLQPWVMGGNVGKRGESPWQALILN-HLGR 218

  Fly   132 YVAGGALIAPHVVITARQRTENMTASQLVVRAGEWD-FSTKTEQLPSVDVPIRSIVRHPGFNLEN 195
            :..||.||..:.|:||....|  |:|:..||.|::. |..:..:   |.:|::..:.||.:|...
Zfish   219 FHCGGVLIDENWVLTAAHCLE--TSSKFSVRLGDYQRFKFEGSE---VTLPVKQHISHPQYNPIT 278

  Fly   196 GANNVALVFLRRSLTSSRHINPICMPSAPKNFDFSR---------CIFTGWGKNSFDDPSYMNVL 251
            ..|::||:.|...:..|.:|.|.|:||    .:.::         .|.||||||:....||.:.|
Zfish   279 VDNDIALLRLDGPVKFSTYILPACLPS----LELAKRMLHRNGTVTIITGWGKNNQSATSYNSTL 339

  Fly   252 KKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAG--GEPGKDSCEGDGGSPLACAIKDNPQRYE 314
            ..:.||:|..:.|.:.:.    |:  |.::::|||  |:. ||:||||.|.|:.....|.   :.
Zfish   340 HYVELPIVDNKECSRHMM----NN--LSDNMLCAGVLGQV-KDACEGDSGGPMMTLFHDT---WF 394

  Fly   315 LAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            |.|:|::|..||......:||.||:.::||
Zfish   395 LVGLVSWGEGCGQRDKLGIYTKVASYLDWI 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	72/242 (30%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	72/242 (30%)
proca	NP_956650.1	GLA	23..84	CDD:214503
		EGF_CA	85..119	CDD:238011	1/3 (33%)
		FXa_inhibition	128..165	CDD:291342	8/46 (17%)
		Tryp_SPc	195..427	CDD:238113	74/250 (30%)
		Tryp_SPc	197..424	CDD:214473	72/246 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910