DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31780 and CG1299

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	373	Identity:	101/373 - (27%)
Similarity:	166/373 - (44%)	Gaps:	86/373 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 QVQAQGQNAELNQSCGASNEHQCVPRHMCKVKIEFRMAMTYRNLGCVSTAICC------------ 71
            :::::.|:|.......|||.       :|:.|               .|.:||
  Fly   186 ELRSRSQDATFANFLRASNA-------VCQNK---------------GTQVCCPTGQGITNTTPA 228

  Fly    72 PKNLIIKE----PRLIINEPITDPQCGFVNSKGVTFSFREEDTG--LAQEAEVPWMVALL---DA 127
            |..::.|.    ||.::|   .:..|      |.|..:.::..|  ::::...|| :|||   |.
  Fly   229 PSQIVPKNTDEIPRRLLN---VEEGC------GSTVGYFKKIVGGEVSRKGAWPW-IALLGYDDP 283

  Fly   128 RTSSYVAGGALIAPHVVITA----RQRTENMTASQLVVRAGEWDFSTKTEQLPSVDVPIRSIVRH 188
            ..|.:..||.||....|:||    ||..:       .||.||.|.||.|| ...||:.|...|.|
  Fly   284 SGSPFKCGGTLITARHVLTAAHCIRQDLQ-------FVRLGEHDLSTDTE-TGHVDINIARYVSH 340

  Fly   189 PGFNLENGANNVALVFLRRSLTSSRHINPICMPSA----PKNFDFSRCIFTGWGKNSFDDPSYMN 249
            |.:|..||.:::|:::|.|::..:..|.|||:|..    .|::........|||| :.:......
  Fly   341 PDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGK-TMEGGESAQ 404

  Fly   250 VLKKISLPVVQRRTCEQQL---RLYYGNDFELDNSLMCAGG-EPGKDSCEGDGGSPLACAIKDNP 310
            ||.::.:|:...:.|.|..   :.|:..| :.|.:::|||. ..|||:|:||.|.||..     |
  Fly   405 VLNELQIPIYDNKVCVQSYAKEKRYFSAD-QFDKAVLCAGVLSGGKDTCQGDSGGPLML-----P 463

  Fly   311 QRYE------LAGIVNFGVDCGLPGVPAVYTNVANVIEWITLTTVNMP 352
            :.|:      |.|:|::|:.|..|.||.||::....::||.....:.|
  Fly   464 EPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWIIQQVQDTP 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	79/251 (31%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	79/251 (31%)
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	8/51 (16%)
		Tryp_SPc	260..503	CDD:214473	80/258 (31%)
		Tryp_SPc	261..503	CDD:238113	80/257 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910