DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and f9a

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_878288.2	Gene:	f9a / 359826	ZFINID:	ZDB-GENE-030714-2	Length:	503	Species:	Danio rerio

Alignment Length:	402	Identity:	106/402 - (26%)
Similarity:	153/402 - (38%)	Gaps:	106/402 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GQNAEL--NQSCGASN---EHQCV--PRH-----------------MCKVKIEFRMAMT------ 58
            |:|.|:  .:.|...|   ||.||  ..|                 .|:..::|....|
Zfish   116 GKNCEIVTAKKCDVDNGGCEHFCVLLESHKTQCQCAYGYKLSEDGLTCEPIVKFPCGKTSKPAVK 180

  Fly    59 -------------YRNLGCVST-AICCPKNLI-------IKE---------PRLIINEPITDPQC 93
                         :.|:...|| :|..|.||.       |||         |:....|.:|.|..
Zfish   181 TYGTASVTNTTAQFSNMTVKSTSSIPKPDNLTNPTNSKDIKEKLAPPRAKLPKWAFEEYLTSPAP 245

  Fly    94 GFVNSKGVTFSFREEDTGLAQEAEVPWMVALLDARTSSYVAGGALIAPHVVITARQRTENMTASQ 158
            .....|.     |......|...|:||.|||:...|.....||:::.|..||||...........
Zfish   246 TVSGPKS-----RIIGGNSALPGEIPWQVALVSRSTQQVFCGGSILNPLWVITAAHCLLGNHNGS 305

  Fly   159 LVVRAGEWDFS--TKTEQLPSVDVPIRSIVRHPGFNLENGANN--VALVFLRRSLTSSRHINPIC 219
            ..:|.||.|.|  ..|||    :|.:..::.||.:|.:....|  :||:.||..:..:..:.|||
Zfish   306 FYIRVGEHDVSKIEGTEQ----NVDVIKLISHPRYNSKVSLFNHDIALLRLRSPIRLTPTVRPIC 366

  Fly   220 M-PSAPKNFDFSRCIF--------TGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGND 275
            : |..     ||..:.        :|||:..|...| ...|:||.||.|.|..|::      .:.
Zfish   367 LGPMV-----FSNTLLQSGTLATVSGWGRVRFQGRS-AATLQKIELPYVDRTVCKE------SSS 419

  Fly   276 FELDNSLMCAG-GEPGKDSCEGDGGSPLACAIKDNPQRYE----LAGIVNFGVDCGLPGVPAVYT 335
            ..:.:.:.||| .:..||:|:||.|.|       :..||.    |.||:::|.:|...|...|||
Zfish   420 DPITHFMFCAGHSDSPKDACQGDSGGP-------HVMRYHNTWFLTGIISWGEECAKKGKYGVYT 477

  Fly   336 NVANVIEWITLT 347
            .|.|...||..|
Zfish   478 QVGNYYRWIQHT 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	74/248 (30%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	74/248 (30%)
f9a	NP_878288.2	GLA	19..83	CDD:214503
		EGF_CA	84..120	CDD:238011	2/3 (67%)
		FXa_inhibition	127..163	CDD:291342	7/35 (20%)
		Tryp_SPc	253..486	CDD:214473	75/255 (29%)
		Tryp_SPc	254..489	CDD:238113	76/257 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910