DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and Corin

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_610297.2	Gene:	Corin / 35691	FlyBaseID:	FBgn0033192	Length:	1397	Species:	Drosophila melanogaster

Alignment Length:	255	Identity:	69/255 - (27%)
Similarity:	122/255 - (47%)	Gaps:	28/255 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 PWMVALLDARTSSYVAGGALIAPHVVITARQRTENMTASQL--------VVRAGEWDFSTKTEQL 175
            |::.|:|......:...|.||:...|:||.....|.:...|        |.|...:.:|.:
  Fly  1116 PFLAAILGGPEKIFYCAGVLISDQWVLTASHCVGNYSVIDLEDWTIQLGVTRRNSFTYSGQ---- 1176

  Fly   176 PSVDVPIRSIVRHPGFNLENG-ANNVALVFLRRSLTSSRHINPICM--PSAPKNFDFSRCIFTGW 237
               .|.:::::.||.:|:... .|::||..|...:....|:.|:|:  ||.......:.|...||
  Fly  1177 ---KVKVKAVIPHPQYNMAIAHDNDIALFQLATRVAFHEHLLPVCLPPPSVRNLHPGTLCTVIGW 1238

  Fly   238 GKNSFDDP--SYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAG-GEPGKDSCEGDGG 299
            ||....||  :|..::.::.:|::.|..|::.|     ::..:...::||| .:.|||:|:||.|
  Fly  1239 GKREDKDPKSTYEYIVNEVQVPIITRNQCDEWL-----DNLTVSEGMVCAGFDDGGKDACQGDSG 1298

  Fly   300 SPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI--TLTTVNMPLPEER 357
            .||.|.......|:.:.|||::|:.|..|.:|.||.||...:.||  .:...:.|:.|:|
  Fly  1299 GPLLCPYPGEKNRWFVGGIVSWGIMCAHPRLPGVYANVVQYVPWIQEQIAKHSRPIKEDR 1358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	64/238 (27%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	64/238 (27%)
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549
		LDLa	911..942	CDD:238060
		LDLa	945..979	CDD:238060
		SR	980..>1034	CDD:214555
		SRCR	992..1086	CDD:278931
		Tryp_SPc	1103..1343	CDD:214473	64/238 (27%)
		Tryp_SPc	1104..1346	CDD:238113	66/241 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910