DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and prss60.3

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	308	Identity:	81/308 - (26%)
Similarity:	137/308 - (44%)	Gaps:	55/308 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 LGCVS-TAICCPKNLIIKEPRLIINEPITDPQCGFVNSKGVTFSFREEDTGLAQEAEVPWMVALL 125
            |.|.: |.:.|.|. .:.:..:....|:.....|.||               |.....||.|:|.
Zfish     6 LTCATLTLLICVKG-SLSQLNVCGQAPLNTRIVGGVN---------------ASPGSWPWQVSLH 54

  Fly   126 DARTSSYVAGGALIAPHVVITARQRTENMTASQLVVRAGEWDFSTKTEQLPSVDVPIRSIVR--- 187
            ..:...:..||:||:...|:||......::.:.|||..|.     :|:|..::....|::.:
Zfish    55 SPKYGGHFCGGSLISSEWVLTAAHCLSGVSETTLVVYLGR-----RTQQGINIYETSRNVAKSFV 114

  Fly   188 HPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFS---RCIFTGWGKNSFDDPSYMN 249
            |..:|.....|::||:.|..::|.:.:|.|:|:  |.:|..:|   ....||||    |..:.:|
Zfish   115 HSSYNSNTNDNDIALLRLSSAVTFTNYIRPVCL--AAQNSVYSAGTSSWITGWG----DIQAGVN 173

  Fly   250 -----VLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAG-GEPGKDSCEGDGGSPLA---CA 305
                 :|::..:|||....|...|     ....:.|:::||| .:.|||:|:||.|.|:.   |.
Zfish   174 LPAPGILQETMIPVVANDRCNALL-----GSGTVTNNMICAGLTQGGKDTCQGDSGGPMVTRLCT 233

  Fly   306 IKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI-TLTTVNMP 352
            :      :..|||.::|..|..|..|.|||.|:....|| :..::|.|
Zfish   234 V------WVQAGITSWGYGCADPNSPGVYTRVSQYQSWISSKISLNKP 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	68/245 (28%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	68/245 (28%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	73/269 (27%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587607
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930