DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and AgaP_AGAP009006

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_552907.3	Gene:	AgaP_AGAP009006 / 3291875	VectorBaseID:	AGAP009006	Length:	401	Species:	Anopheles gambiae

Alignment Length:	360	Identity:	82/360 - (22%)
Similarity:	134/360 - (37%)	Gaps:	86/360 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 QCVPRHMCK-------VKIEFRMAMTY------RNLG-CV--------------------STA-- 68
            :||.||:.:       |..|.::|:.|      |..| ||                    .||
Mosquito    73 ECVIRHISRRELDTSLVAPELKLALDYICEASDREAGVCVHIDHCSHRALAKDVVKVCTNETAPI 137

  Fly    69 ICCPKNLIIKEPRL-IINEPITDPQ------CGFVNSKGVTFSFREEDTGLAQEAEVPWMVALLD 126
            :|||.|..|....| ::.|..|:.|      ..||..:|.....  ||........:.|.|   :
Mosquito   138 VCCPVNSFIATAHLPLLTECETNYQRFRKKYADFVGDRGTAQPL--EDGAHPHSVMIGWKV---N 197

  Fly   127 ARTSSYVAGGALIAPHVVITARQRTENMTASQLVVRAGEWDFSTKTEQLPSVDVPIRSIVRHPGF 191
            ...:::...|.||..:.|:|. ....||      |..||.:.:...:....: :.::..:|:|.:
Mosquito   198 KTATAWHCTGTLINLNTVLTT-AGCANM------VSVGETNVARIYDGAAQI-IRVKETIRYPSY 254

  Fly   192 NLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFSRCIFTGWGKNSFDDPSYMNVLKKISL 256
            |.:...|::|::.|...:..:.:..|.|:..     |.:|..:.| .:..||..|    |.....
Mosquito   255 NAKTHDNDIAVLKLESDVLVNENAIPACLWR-----DLNRTPYYG-QEVHFDGQS----LTARDK 309

  Fly   257 PVVQRRTCEQQLRLYYGNDFELDNSLMCAGGEPGKDSCEGDGGSPLACAIKDNP----QRYE--- 314
            .||..|.|:     .:.:..||.|..:|.    .:.....||.....|..|.||    ||..
Mosquito   310 NVVHNRDCQ-----LFTSHTELTNDQLCW----QEFRLRPDGADAPNCGRKGNPFITLQRTNNIY 365

  Fly   315 ---LAGIVNFGVDCGLPGVPAVYTNVANVIEWITL 346
               |.|:.::...|. .|.|.|.|.:::.|.||:|
Mosquito   366 LPYLVGLYSYDRQCA-GGEPIVATRISSYINWISL 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	51/240 (21%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	51/240 (21%)
AgaP_AGAP009006	XP_552907.3	Tryp_SPc	<1..64	CDD:304450
		Tryp_SPc	184..398	CDD:304450	52/244 (21%)
		Tryp_SPc	184..397	CDD:214473	51/243 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910