DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and f2

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_005169022.1	Gene:	f2 / 325881	ZFINID:	ZDB-GENE-030131-4606	Length:	635	Species:	Danio rerio

Alignment Length:	270	Identity:	75/270 - (27%)
Similarity:	130/270 - (48%)	Gaps:	30/270 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 NSKGVTFSFREEDTGLAQEAEV---PWMVALLDARTSSYVAGGALIAPHVVITARQ------RTE 152
            |.|.:..|:.........||||   ||.|.|........:.|.:||:...::||..      ..:
Zfish   361 NEKELLMSYTGSRIVGGDEAEVASAPWQVMLYKRSPQELLCGASLISDEWILTAAHCILYPPWNK 425

  Fly   153 NMTASQLVVRAGEWDFSTKTEQLPSVDVPIRSIVRHPGFNLENGAN-NVALVFLRRSLTSSRHIN 216
            |.|.:.::||.|:.. .||.|:.....|.|..|:.||.:|.:...| ::||:.:::.:..:..|:
Zfish   426 NFTINDIIVRLGKHS-RTKYERGIEKIVAIDEIIVHPKYNWKENLNRDIALLHMKKPVVFTSEIH 489

  Fly   217 PICMP--SAPKNFDFS--RCIFTGWG--KNSF-DDPSYM-NVLKKISLPVVQRRTCEQQLRLYYG 273
            |:|:|  |..||..|:  :...||||  :.|: .:|:.: .||::|.||:|.:..|.....:.
Zfish   490 PVCLPTKSIAKNLMFAGYKGRVTGWGNLRESWTSNPTNLPTVLQQIHLPIVDQSICRNSTSVI-- 552

  Fly   274 NDFELDNSLMCAGGEPGK----DSCEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVY 334
                :.:::.|||.:|..    |:||||.|.|.......:.:.|:: |||::|..|...|....|
Zfish   553 ----ITDNMFCAGYQPDDSKRGDACEGDSGGPFVMKSPSDNRWYQI-GIVSWGEGCDRDGKYGFY 612

  Fly   335 TNVANVIEWI 344
            |::..:..|:
Zfish   613 THLFRMRRWM 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	71/252 (28%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	71/252 (28%)
f2	XP_005169022.1	GLA	39..100	CDD:214503
		KR	126..206	CDD:214527
		KR	228..309	CDD:214527
		Thrombin_light	326..373	CDD:286482	3/11 (27%)
		Tryp_SPc	373..621	CDD:214473	71/255 (28%)
		Tryp_SPc	374..625	CDD:238113	72/257 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910