DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and Tmprss11g

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_796136.2	Gene:	Tmprss11g / 320454	MGIID:	2444058	Length:	417	Species:	Mus musculus

Alignment Length:	272	Identity:	77/272 - (28%)
Similarity:	128/272 - (47%)	Gaps:	32/272 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 EPITDPQCGFVNSKGVTFS--FREEDTGLAQEAEVPWMVALLDARTSSYVAGGALIAPHVVITAR 148
            |.|.:..||    .|:.:.  .|..|...|.:|..||..:|  .....::.|.:||....::|:.
Mouse   167 EHILNSDCG----SGMEYPPIARIADGKPADKASWPWQSSL--QVEGIHLCGASLIGSQWLVTSA 225

  Fly   149 QRTENMTASQLVVRAGEWDFS-TKTEQLPSVDVPIRSIVRHPGFNLENGANNVALVFLRRSLTSS 212
            ...:|....:|      |..| .:|...|.....:.||:.|..:......:::|:|.|...:..|
Mouse   226 HCFDNYKNPKL------WTVSFGRTLSSPLTTRKVESIIVHENYASHKHDDDIAVVKLSSPVLFS 284

  Fly   213 RHINPICMPSA-----PKNFDFSRCIFTGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYY 272
            .:::.:|:|.|     ||    |:...||||....:.| :.|.|:::.:.::....| .|:.:|.
Mouse   285 ENLHRVCLPDATFQVLPK----SKVFVTGWGALKANGP-FPNSLQEVEIEIISNDVC-NQVNVYG 343

  Fly   273 GNDFELDNSLMCAGGEPGK-DSCEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTN 336
            |   .:.:.::|||...|| |:||||.|.||  .|.||..::.|.|||::|:|||....|.:||.
Mouse   344 G---AISSGMICAGFLTGKLDACEGDSGGPL--VISDNRNKWYLLGIVSWGIDCGKENKPGIYTR 403

  Fly   337 VANVIEWITLTT 348
            |.:..:||...|
Mouse   404 VTHYRDWIKSKT 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	67/237 (28%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	67/237 (28%)
Tmprss11g	NP_796136.2	SEA	48..142	CDD:279699
		Tryp_SPc	185..411	CDD:214473	69/244 (28%)
		Tryp_SPc	186..414	CDD:238113	70/246 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910