DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and F12

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_001014028.1	Gene:	F12 / 306761	RGDID:	1359175	Length:	603	Species:	Rattus norvegicus

Alignment Length:	234	Identity:	70/234 - (29%)
Similarity:	114/234 - (48%)	Gaps:	18/234 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 PWMVALLDARTSSYVAGGALIAPHVVITARQRTENMTA-SQLVVRAGEWDFSTKTEQLPSVDVPI 182
            |::.||...  .|:.| |:||.|..|:||....:...| .:|.|..|:...:...|:..:  :.:
  Rat   374 PYIAALYWG--DSFCA-GSLIDPCWVLTAAHCLQKRPAPEELTVVLGQDRHNQSCERCQT--LAV 433

  Fly   183 RSIVRHPGFNLENGANNVALVFLRRSLTS----SRHINPICMPS--APKNFDFSRCIFTGWGKNS 241
            .|...|.||:.:...:::||:.||....|    |.|:.|:|:||  ||.: :...|...|||...
  Rat   434 HSYRLHEGFSSKTYQHDLALLRLRGRKNSCAILSPHVQPVCLPSSAAPPS-ETVLCEVAGWGHQF 497

  Fly   242 FDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGG-EPGKDSCEGDGGSPLACA 305
            .....|...|::..:|.:....|...  ..:|:  .:...::|||. |.|.|:|:||.|.||.|.
  Rat   498 EGAEEYATFLQEAQVPFISLDRCSSS--NVHGD--AILPGMLCAGFLEGGADACQGDSGGPLVCD 558

  Fly   306 IKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            .....::..|.|::::|..||....|.|||:|||.::||
  Rat   559 EGVTERQLTLRGVISWGSGCGDRNKPGVYTDVANYLDWI 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	68/232 (29%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	68/232 (29%)
F12	NP_001014028.1	FN2	40..87	CDD:238019
		EGF_CA	95..130	CDD:238011
		FN1	132..170	CDD:238018
		EGF	177..207	CDD:278437
		Kringle	216..294	CDD:278480
		Tryp_SPc	361..597	CDD:214473	68/232 (29%)
		Tryp_SPc	362..600	CDD:238113	70/234 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910