DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and HABP2

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_004123.1	Gene:	HABP2 / 3026	HGNCID:	4798	Length:	560	Species:	Homo sapiens

Alignment Length:	245	Identity:	76/245 - (31%)
Similarity:	116/245 - (47%)	Gaps:	33/245 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 PWMVALLD------ARTSSYVAGGALIAPHVVITARQRTENMTASQLVVRAGEWDFSTKTEQLPS 177
            ||..:|..      :....:..|||||.|..|:||...|:..| ..|.|..|:.|.  |.|:...
Human   326 PWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKT-RHLKVVLGDQDL--KKEEFHE 387

  Fly   178 VDVPIRSIVRHPGFNL--ENGANNVALVFLR----RSLTSSRHINPICMP--SAPKNFDFSRCIF 234
            ....:..|.::..:|.  |...|::||:.|:    .....|:::..:|:|  |.|..   |.|..
Human   388 QSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALESKYVKTVCLPDGSFPSG---SECHI 449

  Fly   235 TGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGG--EPGKDSCEGD 297
            :|||.......|...:..|:.|  :....|..: :||   |..:|:|::|||.  :||:|:|:||
Human   450 SGWGVTETGKGSRQLLDAKVKL--IANTLCNSR-QLY---DHMIDDSMICAGNLQKPGQDTCQGD 508

  Fly   298 GGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWITLT 347
            .|.||.|. ||.  .|.:.|||::|::||..  |.|||.|...:.||..|
Human   509 SGGPLTCE-KDG--TYYVYGIVSWGLECGKR--PGVYTQVTKFLNWIKAT 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	73/240 (30%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	73/240 (30%)
HABP2	NP_004123.1	EGF	77..106	CDD:306513
		KR	191..277	CDD:238056
		Tryp_SPc	314..553	CDD:238113	75/243 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910