DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and F10

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_058839.1	Gene:	F10 / 29243	RGDID:	61850	Length:	482	Species:	Rattus norvegicus

Alignment Length:	304	Identity:	74/304 - (24%)
Similarity:	130/304 - (42%)	Gaps:	39/304 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 KEPRLIINEPITDPQCGFVNSKGVTFSFREEDTGLAQEAEVPWMVALLDARTSSYVAGGALIAPH 142
            :.|..::|...|:|:   .||..|......::   .:..|.||...|.....:....||.::...
  Rat   209 ESPSELLNLNKTEPE---ANSDDVIRIVGGQE---CKRGECPWQALLFSDEETDGFCGGTILNEF 267

  Fly   143 VVITARQRTENMTASQLVVRAGEWDFSTKTEQLPSVDVPIRSIVRHPGFNLENGANNVALVFLRR 207
            .::||......  |.:..||.|  |.:|:.|....:...:..|::|..|..:....::|::.|:.
  Rat   268 YILTAAHCLHQ--AKRFKVRVG--DLNTEQEDGGEMVHEVDMIIKHNKFQRDTYDFDIAMLRLKT 328

  Fly   208 SLTSSRHINPICMPSAPKNFDFSRC--------IFTGWGKNSFDDPSYMNVLKKISLPVVQRRTC 264
            .:|...::.|.|:|..    |::..        |.:|:|: :.:......|||.:.:|.|.|.||
  Rat   329 PITFRENVAPACLPQK----DWAEATLMTQKTGIVSGFGR-THEKGRQSKVLKMMEVPYVDRNTC 388

  Fly   265 EQQLRLYYGNDFELDNSLMCAGGE-PGKDSCEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLP 328
                ||  ...|.:..::.|||.: ..:|:|:||.|.|.....||.   |.:.|||::|..|...
  Rat   389 ----RL--STSFSITQNMFCAGYDAKQEDACQGDSGGPHVTRFKDT---YFVTGIVSWGEGCARK 444

  Fly   329 GVPAVYTNVANVIEWITLTTVNMPLPEEREEVPYASPTLSAGPY 372
            |...:||.|...::||..:.      :.|......:|.|:..||
  Rat   445 GKYGIYTKVTAFLKWIDRSM------KARVGPTSETPRLTHPPY 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	60/239 (25%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	60/239 (25%)
F10	NP_058839.1	GLA	23..84	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:405372
		Tryp_SPc	232..462	CDD:238113	62/250 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910