DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and Tmprss15

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_038944148.1	Gene:	Tmprss15 / 288291	RGDID:	1311046	Length:	1028	Species:	Rattus norvegicus

Alignment Length:	249	Identity:	77/249 - (30%)
Similarity:	118/249 - (47%)	Gaps:	49/249 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 PWMVALL--DARTSSYVAGGALI-------APHVV------------ITARQRTENMTASQLVVR 162
            ||:|||.  |......:.|.:|:       |.|.|            :.......|:|:.|:|.|
  Rat   801 PWVVALYYRDRSGDRLLCGASLVSSDWLVSAAHCVYRRNLDPTRWTAVLGLHMQSNLTSPQVVRR 865

  Fly   163 AGEWDFSTKTEQLPSVDVPIRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNF 227
            .                  :..||.:|.::.....|::|::.|...:..:.:|.|||:|...:.|
  Rat   866 V------------------VDRIVINPHYDKRRKVNDIAMMHLEFKVNYTDYIQPICLPEENQTF 912

  Fly   228 DFSR-CIFTGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAG-GEPG 290
            ...| |...|||.|..:..|.::|||:..:|:|....|:|||     .::::..|::||| .|.|
  Rat   913 TPGRMCSIAGWGYNKINAGSTVDVLKEADVPLVSNEKCQQQL-----PEYDITESMLCAGYEEGG 972

  Fly   291 KDSCEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            .|||:||.|.||.|  ::| .|:.|.|:.:|||.|.||..|.||..|:..||||
  Rat   973 TDSCQGDSGGPLMC--QEN-NRWFLVGVTSFGVQCALPNHPGVYARVSQFIEWI 1023

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	75/247 (30%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	75/247 (30%)
Tmprss15	XP_038944148.1	SEA	54..155	CDD:214554
		LDLa	188..221	CDD:238060
		CUB	229..335	CDD:412131
		MAM	351..507	CDD:395504
		CUB	528..635	CDD:395345
		LDLa	647..681	CDD:238060
		Tryp_SPc	789..1025	CDD:238113	77/249 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910