DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and Tmprss7

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_001099352.2	Gene:	Tmprss7 / 288118	RGDID:	1304655	Length:	829	Species:	Rattus norvegicus

Alignment Length:	303	Identity:	80/303 - (26%)
Similarity:	135/303 - (44%)	Gaps:	40/303 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 RNLGCVSTAICCPKNLIIKEPRL----IINEPITDPQCGFVNSKGVTFSFREEDTGLAQEAEVPW 120
            |::.|.:....|..::..::...    |::.|....:.|...|:...|..|......:||...||
  Rat   541 RSIPCTNRTFKCGNDICFRKQNAQCDGIVDCPDRSDEEGCGCSRSSPFLHRVVGGSDSQEGTWPW 605

  Fly   121 MVALLDARTSSYVAGGALIAPHVVITAR-----QRTEN---MTASQLVVRAGEWDFSTKTEQLPS 177
            .|:|  ....|...|.::|:...:::|.     .|..:   .||...:...|...|.:
  Rat   606 QVSL--HFVGSAHCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYVQGNAKFVS------- 661

  Fly   178 VDVPIRSIVRHPGFNLENGANNVALVFLRRSL----TSSRHINPICMPSAPKNF-DFSRCIFTGW 237
               |:|.||.|..:|.:....::||  |:.|:    |..:.|.|||:|...:.. ...:|..|||
  Rat   662 ---PVRRIVVHEYYNSQTFDYDIAL--LQLSIAWPETLRQLIQPICIPPVGQRVRSGEKCWVTGW 721

  Fly   238 GKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGGEPGK-DSCEGDGGSP 301
            |:....|.....:|::..:.::.:..|...    ||   .:.:.::|||...|| |:|:||.|.|
  Rat   722 GRRHEADSKGSPILQQAEVELIDQTVCVST----YG---IITSRMLCAGVMSGKSDACKGDSGGP 779

  Fly   302 LACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            |:|..|.: .::.|.|||::|..||.|..|.|||.|:|.:.||
  Rat   780 LSCRRKSD-GKWILTGIVSWGYGCGRPNFPGVYTRVSNFVPWI 821

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	69/244 (28%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	69/244 (28%)
Tmprss7	NP_001099352.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	30..49
		SEA	94..190	CDD:279699
		CUB	<257..345	CDD:238001
		LDLa	470..504	CDD:238060
		LDLa	545..580	CDD:238060	4/34 (12%)
		Tryp_SPc	591..821	CDD:214473	70/251 (28%)
		Tryp_SPc	592..823	CDD:238113	71/252 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910