DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and Plau

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_037217.3	Gene:	Plau / 25619	RGDID:	3343	Length:	432	Species:	Rattus norvegicus

Alignment Length:	243	Identity:	77/243 - (31%)
Similarity:	111/243 - (45%)	Gaps:	30/243 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 PWMVALL----DARTSSYVAGGALIAPHVVITARQRTENM-TASQLVVRAGEWDFSTKTEQLP-S 177
            ||..|:.    .....|:..||:||:|..|.:|.....|. ...:.||..|:   |.:....| .
  Rat   191 PWFAAIYLKNKGGSPPSFKCGGSLISPCWVASATHCFVNQPKKEEYVVYLGQ---SKRNSYNPGE 252

  Fly   178 VDVPIRSIVRHPGFNLENGA--NNVALVFLRRS----LTSSRHINPICMP----SAPKNFDFSRC 232
            :...:..::.|..|:.|..|  |::||:.:|.|    ...||.|..||:|    .||...|   |
  Rat   253 MKFEVEQLILHEDFSDETLAFHNDIALLKIRTSTGQCAQPSRTIQTICLPPRFGDAPFGSD---C 314

  Fly   233 IFTGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGGEPGK-DSCEG 296
            ..||:|:.|..|..|...||...:.::....|:|.  .|||:  |::..::||.....| |||.|
  Rat   315 EITGFGQESATDYFYPKDLKMSVVKIISHEQCKQP--HYYGS--EINYKMLCAADPEWKTDSCSG 375

  Fly   297 DGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            |.|.||.|.|...|   .|:|||::|..|.....|.|||.|:..:.||
  Rat   376 DSGGPLICNIDGRP---TLSGIVSWGSGCAEKNKPGVYTRVSYFLNWI 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	75/241 (31%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	75/241 (31%)
Plau	NP_037217.3	Binds urokinase plasminogen activator surface receptor	34..57
		KR	67..152	CDD:238056
		Connecting peptide	152..178
		Tryp_SPc	178..420	CDD:214473	75/241 (31%)
		Tryp_SPc	179..423	CDD:238113	77/243 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910