DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and Klkb1

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	258	Identity:	74/258 - (28%)
Similarity:	126/258 - (48%)	Gaps:	17/258 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 CGFVNSKGVTFSFREEDTGLAQEA--EVPWMVAL-LDARTSSYVAGGALIAPHVVITARQRTENM 154
            |..|.|...|........|....:  |.||.|:| :...:.:::.||::|....::||....:.:
  Rat   375 CKVVESSDCTTKINARIVGGTNSSLGEWPWQVSLQVKLVSQNHMCGGSIIGRQWILTAAHCFDGI 439

  Fly   155 TASQL-VVRAGEWDFSTKTEQLPSVDVPIRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPI 218
            ....: .:..|..:.|..|.:.|...  |:.::.|..:.:..|:.::||:.|:..|..:....||
  Rat   440 PYPDVWRIYGGILNLSEITNKTPFSS--IKELIIHQKYKMSEGSYDIALIKLQTPLNYTEFQKPI 502

  Fly   219 CMPS-APKNFDFSRCIFTGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSL 282
            |:|| |..|..::.|..||||... :.....|:|:|.::|:|....|:::.|     |:.:...:
  Rat   503 CLPSKADTNTIYTNCWVTGWGYTK-ERGETQNILQKATIPLVPNEECQKKYR-----DYVITKQM 561

  Fly   283 MCAG-GEPGKDSCEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            :||| .|.|.|:|:||.|.||.|   .:..|::|.||.::|..|.....|.|||.||..|:||
  Rat   562 ICAGYKEGGIDACKGDSGGPLVC---KHSGRWQLVGITSWGEGCARKEQPGVYTKVAEYIDWI 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	67/236 (28%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	67/236 (28%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519	74/258 (29%)
		Tryp_SPc	390..621	CDD:214473	68/241 (28%)
		Tryp_SPc	391..621	CDD:238113	68/240 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910