DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_006510195.1	Gene:	Tmprss13 / 214531	MGIID:	2682935	Length:	561	Species:	Mus musculus

Alignment Length:	425	Identity:	108/425 - (25%)
Similarity:	164/425 - (38%)	Gaps:	120/425 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IIAIVSLILVAGQVQAQGQNA---------------ELNQSCGASNEHQCVPRHM--------CK 48
            |..::||||:.|..:.|....               |..:||         |.|.        ||
Mouse   157 ISLVISLILLYGGRETQSPRGTAVYFWRGHTGIKYKEPLESC---------PIHAVRCDGVVDCK 212

  Fly    49 VKIEFRMAMTYRNLGCVS------------------TAIC------------CPK---------- 73
            :|.:        .||||.                  ..:|            |.:
Mouse   213 MKSD--------ELGCVRFDWDKSLLKVYSGSSGEWLPVCSSSWNDTDSKRTCQQLGFDSAYRTT 269

  Fly    74 ---------NLIIKEPRLIINEPITDPQC---GFVNSKGVTFSFREEDTG------LAQEAEVPW 120
                     :.::.|....|.|.:...||   .:|:.:......|.. ||      |..|::.||
Mouse   270 EVAHRDITSSFLLSEYNTTIQESLYRSQCPSRRYVSLQCSHCGLRAM-TGRIVGGALTSESKWPW 333

  Fly   121 MVALLDARTSSYVAGGALIAPHVVITARQRTENMTASQLV----VRAGEWDFSTKTEQLPSVDVP 181
            .|:|....|  ::.||.||....|:|| .....:|..:|:    |.||    ::...|||.. ..
Mouse   334 QVSLHFGTT--HICGGTLIDAQWVLTA-AHCFFVTREKLLEGWKVYAG----TSNLHQLPEA-AS 390

  Fly   182 IRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFSR-CIFTGWGKNSFDDP 245
            |..|:.:..:..|....::||:.|.:.||.|.||:|.|:|...:.|..:. |..||:||....|.
Mouse   391 ISQIIINGNYTDEQDDYDIALIRLSKPLTLSAHIHPACLPMHGQTFGLNETCWITGFGKTKETDE 455

  Fly   246 SYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGG-EPGKDSCEGDGGSPLACAIKDN 309
            .....|:::.:.::..:.|...| :|   |..|...:||||. ..|:|||:||.|.||.|   :.
Mouse   456 KTSPFLREVQVNLIDFKKCNDYL-VY---DSYLTPRMMCAGDLRGGRDSCQGDSGGPLVC---EQ 513

  Fly   310 PQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            ..|:.|||:.::|..||....|.|||.|..|:.||
Mouse   514 NNRWYLAGVTSWGTGCGQKNKPGVYTKVTEVLPWI 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	75/236 (32%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	75/236 (32%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065
		LDLa	<204..220	CDD:238060	4/23 (17%)
		SRCR_2	225..314	CDD:373897	8/88 (9%)
		Tryp_SPc	319..548	CDD:214473	76/243 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910