DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and Tmprss11a

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_006534903.1	Gene:	Tmprss11a / 194597	MGIID:	2684853	Length:	392	Species:	Mus musculus

Alignment Length:	235	Identity:	71/235 - (30%)
Similarity:	109/235 - (46%)	Gaps:	22/235 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 PWMVALLDARTSSYVAGGALIAPHVVITARQ--RTENMTASQLVVRAGEWDFSTKTE-QLPSVDV 180
            ||.|:|  .|::.:..||.||....|:||..  ||.:        ...:|..|..|. ..|.:..
Mouse   173 PWQVSL--QRSNIHQCGGTLIGNMWVVTAAHCFRTNS--------NPRQWTLSFGTTINPPLMKR 227

  Fly   181 PIRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFSRCIF-TGWGKNSFDD 244
            .:|.|:.|..:......:::|||.....:|.|..:..||:|....:|..:..:: ||:|...:..
Mouse   228 DVRRIIMHERYRPPARDHDIALVQFSPRVTFSDEVRRICLPEPSASFPPNSTVYITGFGALYYGG 292

  Fly   245 PSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGGEPGK-DSCEGDGGSPLACAIKD 308
            .| .|.|::..:.::....|::  |..|||  |:...:.|||...|. |:|.||.|.||  .|:|
Mouse   293 ES-QNELREARVQIISNDICKK--RHVYGN--EIKRGMFCAGFLEGNYDACRGDSGGPL--VIRD 350

  Fly   309 NPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWITLTT 348
            |...:.|.|||::|.:||....|.|||.|.....||...|
Mouse   351 NKDTWYLIGIVSWGDNCGQKNKPGVYTQVTYYRHWIASKT 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	68/229 (30%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	68/229 (30%)
Tmprss11a	XP_006534903.1	SEA	42..135	CDD:366610
Tmprss11a	XP_006534903.1	Tryp_SPc	161..389	CDD:238113	70/232 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910