DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and Proc

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_006525784.1	Gene:	Proc / 19123	MGIID:	97771	Length:	484	Species:	Mus musculus

Alignment Length:	325	Identity:	83/325 - (25%)
Similarity:	146/325 - (44%)	Gaps:	52/325 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 CGASNEHQCVPRHM-CKVKIEFRMAMTYRNLGCVSTAICCPKNLIIKEPRLIINEPITDPQCGFV 96
            |..:..::....|| ||..:.|......|.:.        .|..|:|....:.:|...||:  .|
Mouse   183 CACAPGYELADDHMRCKSTVNFPCGKLGRWIE--------KKRKILKRDTDLEDELEPDPR--IV 237

  Fly    97 NSKGVTFSFREEDTGLAQEAEVPWMVALLDARTSSYVAGGALIAPHVVITARQRTENMTASQLVV 161
            |..            |.::.:.||...|||:: .....||.||....|:||....|.  ..:|.|
Mouse   238 NGT------------LTKQGDSPWQAILLDSK-KKLACGGVLIHTSWVLTAAHCVEG--TKKLTV 287

  Fly   162 RAGEWDFSTKTEQLPSVDVPIRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKN 226
            |.||:|...:...  .:|:.|:.|:.||.:...:..|::||:.|.:..|.|:.|.|||:|:....
Mouse   288 RLGEYDLRRRDHW--ELDLDIKEILVHPNYTRSSSDNDIALLRLAQPATLSKTIVPICLPNNGLA 350

  Fly   227 FDFSRC----IFTGWG------KNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNS 281
            .:.::.    :.||||      |:...:.::  :|..|.:|:|.|..|.:.::..      :..:
Mouse   351 QELTQAGQETVVTGWGYQSDRIKDGRRNRTF--ILTFIRIPLVARNECVEVMKNV------VSEN 407

  Fly   282 LMCAG--GEPGKDSCEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            ::|||  |:. :|:|:||.|.|:....:..   :.|.|:|::|..||......:||.|.:.::||
Mouse   408 MLCAGIIGDT-RDACDGDSGGPMVVFFRGT---WFLVGLVSWGEGCGHTNNYGIYTKVGSYLKWI 468

Fly 345 344
Mouse 469 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	65/242 (27%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	65/242 (27%)
Proc	XP_006525784.1	GLA	50..110	CDD:214503
		EGF_CA	111..155	CDD:238011
		FXa_inhibition	163..198	CDD:373209	3/14 (21%)
		Tryp_SPc	236..470	CDD:238113	70/262 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910