DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and AgaP_AGAP001366

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_321777.4	Gene:	AgaP_AGAP001366 / 1281814	VectorBaseID:	AGAP001366	Length:	563	Species:	Anopheles gambiae

Alignment Length:	279	Identity:	73/279 - (26%)
Similarity:	111/279 - (39%)	Gaps:	50/279 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 CGFVNSKG---VTFSFREEDTGLAQEAEVPWMVALLDARTS--SYVAGGALIAPHVVITA----- 147
            ||.|..|.   ||..      .:::..:.||..||..:..:  .|:.|..||:....|||
Mosquito   304 CGTVVPKANPLVTHG------TVSERGQFPWHGALYRSTVTELKYLCGATLISRRASITAAHCVT 362

  Fly   148 -RQRTENMTASQLVVRAGEWDFSTKTEQLPSVDVPIRSIVRHPGFNLENGANNVALVFLRRSLTS 211
             .:.::.:.|..|::..|:.|.|....  |..|..||||.....:..|...|::|::.|:..:..
Mosquito   363 LEKSSKPVDAGSLLLYFGKIDLSKWNG--PEEDAQIRSIHIPAQYQHERFFNDIAVLVLKEDIKY 425

  Fly   212 SRHINPICMPSAPKNFD------FSRCIFT-GWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLR 269
            |..:.|:|:    .|||      .::..|. |||.|.....|  :.|....:|||...||
Mosquito   426 SNFVRPVCL----WNFDDDYKTLINKIGFVPGWGYNEHGLVS--SRLSFAQMPVVAHETC----- 479

  Fly   270 LYYGNDF---ELDNSLMCAGGEPGKDSCEGDGGSPLACAIKDNPQRYELAGIVNFGV------DC 325
            ::...||   ...::..|||.:.|...|.||.|..:  ..|.|...| |.|||:...      .|
Mosquito   480 IWSNRDFFSKVTSDTSFCAGFKNGTSVCNGDSGGGM--VFKHNNLWY-LRGIVSVSAALQDRFHC 541

  Fly   326 GLPGVPAVYTNVANVIEWI 344
            ..... .|:|:.|....||
Mosquito   542 DSKHY-VVFTDAAKFTSWI 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	65/254 (26%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	65/254 (26%)
AgaP_AGAP001366	XP_321777.4	GD_N	15..124	CDD:292649
		Tryp_SPc	315..560	CDD:238113	69/268 (26%)
		Tryp_SPc	315..559	CDD:214473	67/266 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910