DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and AgaP_AGAP001415

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_321719.5	Gene:	AgaP_AGAP001415 / 1281762	VectorBaseID:	AGAP001415	Length:	887	Species:	Anopheles gambiae

Alignment Length:	320	Identity:	63/320 - (19%)
Similarity:	96/320 - (30%)	Gaps:	108/320 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AIVS----LILV--AGQVQAQGQNAELNQSCGASNEHQCVPRHMCKVKIEFRMAMTYRNLGCVST 67
            |::|    |::|  :|::|.:|..|:..............|...|        :.|||     ||
Mosquito   394 AVISDGPRLVMVFSSGELQGRGFKAKYTFETEYKIPGTAAPDGTC--------SFTYR-----ST 445

  Fly    68 AICCPKNLIIKEPRLIINEPITDPQCGFV----NSKGVTFSFRE--------EDTGLAQEAEV-- 118
            :   .|......||...|.| ::..|.:|    .::.||..|..        ..||.|..|.|
Mosquito   446 S---RKKGEFNSPRYPSNYP-SETNCSYVFLATPNEQVTIVFDHFKVKADGANTTGGAYGASVCF 506

  Fly   119 -PWM---VALLD------ARTSSYVAGGALIAPH----VVITARQRTENMTASQLVVRAGEWDFS 169
             .|:   |...|      .|..|..|.|.:.:|.    :.:......||: ||....|   :.|.
Mosquito   507 EDWLEMYVLYRDGTDRFLGRYCSLTAPGPVESPRGAVGIRVVLHTDLENV-ASGFKAR---YIFE 567

  Fly   170 TKTEQLPSVDVPIRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFSRCIF 234
            |           .:|:....|.|.....:.:                 :..|:.|.|:|
Mosquito   568 T-----------AKSVFGDCGGNFSGEDSGI-----------------VTSPNFPANYD------ 598

  Fly   235 TGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGGEPGKDSC 294
             |.||.                  :..|.|...:....|....|:.......|||....|
Mosquito   599 -GPGKG------------------LASRACNWYITARIGYKILLNFDYFAIEGEPATRGC 639

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	36/198 (18%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	36/198 (18%)
AgaP_AGAP001415	XP_321719.5	CUB	27..142	CDD:238001
		CUB	159..271	CDD:238001
		CUB	303..422	CDD:238001	8/27 (30%)
		CUB	438..566	CDD:238001	34/148 (23%)
		CUB	576..699	CDD:238001	17/106 (16%)
		LDLa	718..754	CDD:238060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910