DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and AgaP_AGAP011908

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_320621.4	Gene:	AgaP_AGAP011908 / 1280755	VectorBaseID:	AGAP011908	Length:	391	Species:	Anopheles gambiae

Alignment Length:	287	Identity:	73/287 - (25%)
Similarity:	122/287 - (42%)	Gaps:	35/287 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 RLIINEPITDPQCGFVNSKGVTFSFREEDTGLAQEAEVPWMVALLDARTSSYVAGGALIAPHVVI 145
            ||::.....|  ||:..:..:.      ...:|...|...||.|||..|.:....||:|:...|:
Mosquito   136 RLVVQPQECD--CGWSRTAKIV------GGSVAGVNEYTAMVGLLDPLTVNVFCSGAIISSRYVL 192

  Fly   146 TARQRTENM-TASQLVVRAGEWDFSTKTEQLPSVDVPIRSIVRHPGFNLENGANNVALVFLRRSL 209
            ||......: :.|::....|:.|:.:..:...|....|..|:.|..:|.:...|::||:.....:
Mosquito   193 TAAHCARTIPSVSRVQALVGDHDYRSGLDTPYSAIYNIEQIISHEYYNEQTRNNDIALLKTSTEM 257

  Fly   210 TSSRHINPICMPSAPKNFDFS--RCIFTGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYY 272
            ..:|.:.|||:|.....:.|.  .....|||..||..| ...:|:|.:|.|:|...|...    |
Mosquito   258 DFNRGVGPICLPFTYSTYSFGGLSVDIAGWGTTSFGGP-MSTILRKTTLNVLQNANCTAP----Y 317

  Fly   273 GNDFELDNSLMCAGGEPGKDSCEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNV 337
            .||.::....:      |:|||:.|.|.  |..::.:.:.|.: ||:::|..|. ...|:|.|.|
Mosquito   318 VNDQKICTFAV------GRDSCQYDSGG--ALFLRGSQRMYSI-GIISYGSACA-ASTPSVATRV 372

  Fly   338 ANVIEWITLTTVNMPLPEEREEVPYAS 364
            ...:.||...|         .||.|.:
Mosquito   373 TAYLSWIRQNT---------PEVSYCA 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	62/233 (27%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	62/233 (27%)
AgaP_AGAP011908	XP_320621.4	CUB	26..>106	CDD:294042
		Tryp_SPc	153..379	CDD:214473	62/246 (25%)
		Tryp_SPc	154..382	CDD:238113	64/248 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910