DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and AgaP_AGAP010730

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_311444.4	Gene:	AgaP_AGAP010730 / 1272531	VectorBaseID:	AGAP010730	Length:	256	Species:	Anopheles gambiae

Alignment Length:	256	Identity:	96/256 - (37%)
Similarity:	136/256 - (53%)	Gaps:	19/256 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 LAQEAEVPWMVALL-----DARTSSYVAGGALIAPHVVITARQRTENMTASQLVVRAGEWDFSTK 171
            |:|.||.||:|.:|     :|.:..:|.||.||...:|:|....|:..|  .||.|.||||.||.
Mosquito     2 LSQYAEYPWVVYILALKKQEANSGDFVCGGTLIHSRLVVTTAHNTDGKT--DLVARFGEWDISTT 64

  Fly   172 TEQLPS------VDVPIRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFS 230
            .|..|.      .|:.:..:::||.:......|::||:.|..::..:.||.|||:|.....|...
Mosquito    65 KEPFPQQCLFPHQDIDVAEVIKHPQYVFNPIQNDIALLVLAENVQYAAHIRPICLPQPTDEFVGQ 129

  Fly   231 RCIFTGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLY-YGNDFELDNSLMCAGGEPGKDSC 294
            ||:..||||   :...|.||:||::|||:.|..|.:.||.. .|..:.|....:|||||...|.|
Mosquito   130 RCVSNGWGK---ERGVYANVMKKLTLPVIGRANCTRMLRYAGLGPFYTLREGFLCAGGEVAVDMC 191

  Fly   295 EGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWITLTTVNMPLPE 355
            :|||||||||..:..  .|.|||||::|:.||....|.||..|...::|:....|:..|.|
Mosquito   192 KGDGGSPLACQTESG--TYVLAGIVSWGIGCGGFNTPGVYVAVNRYVQWLNEHIVDQALNE 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	91/242 (38%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	91/242 (38%)
AgaP_AGAP010730	XP_311444.4	Tryp_SPc	7..242	CDD:238113	90/241 (37%)
AgaP_AGAP010730	XP_311444.4	Tryp_SPc	7..238	CDD:214473	89/237 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870