DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31780 and Cfi

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_031712.2	Gene:	Cfi / 12630	MGIID:	105937	Length:	603	Species:	Mus musculus

Alignment Length:	347	Identity:	82/347 - (23%)
Similarity:	138/347 - (39%)	Gaps:	91/347 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 GQVQAQGQNAELNQSCGASNEHQ----CVPRHMCKVKIEFRMAMTYRNLGCVSTAICCPKNLIIK 78
            |:.:.:.:..|: .:.|..||.:    .:|:..|.||                      :|...:
Mouse   316 GEAEIETEETEM-LTPGMDNERKRIKSLLPKLSCGVK----------------------RNTHTR 357

  Fly    79 EPRLIINEPITDPQCGFVNSKGVTFSFREEDTGLAQEAEVPWMVALLDARTSS----YVAG-GAL 138
            ..|:|..:|                         |...:.||.||:.|.:..:    |:.| ..|
Mouse   358 RKRVIGGKP-------------------------ANVGDYPWQVAIKDGQRITCGGIYIGGCWIL 397

  Fly   139 IAPHVVITARQRTENMTASQLVVRAGEWDFSTKTEQLPSVDVPIRSIVR---HPGFNLENGANNV 200
            .|.|.|..:|..:..:..:.|     :|       ..|:..:.|:::.|   |..:|.....|::
Mouse   398 TAAHCVRPSRAHSYQVWTALL-----DW-------LKPNSQLGIQTVKRVIVHEKYNGATFQNDI 450

  Fly   201 ALVFLRRSLTSSRHIN-----PICMPSAPKNFD-FSRCIFTGWGKNSFDDPSYMNVLKKISLPVV 259
            ||:.::.. |..:...     |.|:|.:|..|. ..|||.:|||:...:...|.....::.|
Mouse   451 ALIEMKMH-TGKKECELPNSVPACVPWSPYLFQPNDRCIISGWGRGKDNQKVYSLRWGEVDL--- 511

  Fly   260 QRRTCEQQLRLYYGNDFELDNSLMCAGGEPGK-DSCEGDGGSPLACAIKDNPQRYELAGIVNFGV 323
             ...|.|    :|.:.: .:..:.|||...|. |:|:||.|.||.|  :|......:.|||::|.
Mouse   512 -IGNCSQ----FYPDRY-YEKEMQCAGTRDGSIDACKGDSGGPLVC--EDINNVTYVWGIVSWGE 568

  Fly   324 DCGLPGVPAVYTNVANVIEWIT 345
            :||.|..|.|||.|||..:||:
Mouse   569 NCGKPEFPGVYTRVANYFDWIS 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	67/245 (27%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	67/245 (27%)
Cfi	NP_031712.2	FIMAC	46..111	CDD:214493
		SR	117..220	CDD:214555
		SRCR	122..219	CDD:278931
		LDLa	232..261	CDD:238060
		LDLa	264..298	CDD:294076
		Tryp_SPc	360..589	CDD:214473	70/277 (25%)
		Tryp_SPc	361..592	CDD:238113	71/279 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910