Protein Alignment CG31780 and KLK8

DIOPT Version :9

• Sequence 1: NP_723920.1
• Gene: CG31780 / 318937
• FlyBaseID: FBgn0051780
• Length: 464
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 79/304 - (25%)
• Similarity: 126/304 - (41%)
• Gaps: 64/304 - (21%)

  Fly    61 NLGCV-------STAICCPKNLIIKEPRLIINEPITDPQCGFVNSKGVTFSFREEDTGL----AQ 114
            ||.||       |....||:..        .:.|: .|..|        .|..:||..|    .|
Human    38 NLPCVHLNPQWPSQPSHCPRGW--------RSNPL-PPAAG--------HSRAQEDKVLGGHECQ 85

  Fly   115 EAEVPWMVALLDARTSSYVAGGALIAPHVVITARQRTENMTASQLVVRAGEWDFSTKTEQLPSVD 179
            ....||..||...:  ..:.||.|:..:.|:||    .:....:..||.|  |.|.:.:..|..:
Human    86 PHSQPWQAALFQGQ--QLLCGGVLVGGNWVLTA----AHCKKPKYTVRLG--DHSLQNKDGPEQE 142

  Fly   180 VPIRSIVRHPGFN---LENGANNVALVFLRRSLTSSRHINPI-----CMPSAPKNFDFSRCIFTG 236
            :|:...:.||.:|   :|:..:::.|:.||...:....:.||     |.....|      |..:|
Human   143 IPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQK------CTVSG 201

  Fly   237 WGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGGEPGKDSCEGDGGSP 301
            ||..:....::.:.|....:.:..::.||.   .|.|   ::.:.::|||...|.|:|:||.|.|
Human   202 WGTVTSPRENFPDTLNCAEVKIFPQKKCED---AYPG---QITDGMVCAGSSKGADTCQGDSGGP 260

  Fly   302 LACAIKDNPQRYELAGIVNFGVD-CGLPGVPAVYTNVANVIEWI 344
            |.|   |.    .|.||.::|.| ||....|.||||:...::||
Human   261 LVC---DG----ALQGITSWGSDPCGRSDKPGVYTNICRYLDWI 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	63/239 (26%)
		Tryp_SPc	113..344	CDD:238113	63/239 (26%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	64/246 (26%)
		Tryp_SPc	78..300	CDD:238113	66/247 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910