DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and gprin3

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_017951795.1	Gene:	gprin3 / 101733019	XenbaseID:	XB-GENE-6468967	Length:	725	Species:	Xenopus tropicalis

Alignment Length:	444	Identity:	95/444 - (21%)
Similarity:	146/444 - (32%)	Gaps:	141/444 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 IKEPRLIINEPITDPQCGF-VNS--KGVTFSFREEDTGL-----AQEAEVPWMVALLDARTSSYV 133
            :|:..|:  .|:...:.|. |:|  |.......|.|.||     .:||: |.:.:|...:|.|..
Frog   137 VKDNTLV--APLVSAEAGMQVSSDFKNKPLVESEPDKGLDSLLQNKEAD-PSLPSLPTHKTESIN 198

  Fly   134 AG----GALIAPHVVITARQRT--ENMTASQLVVRAGEWDFSTKTEQLPSVDVPIRSIVRHPG-- 190
            :|    ..:|....||||...:  :::|:::....:.|.|...|..:....|.|:.|..:..|
Frog   199 SGTQNASTIIESEGVITAEGESTKDSITSNECHKLSFEKDKIKKENEEVETDPPLPSRFKEMGTM 263

  Fly   191 --FNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFSRCIFTGWGKNSFDDPSYMNVLKK 253
              |:|||.....|.|                  .|..|.:         .|:....||.:....|
Frog   264 TSFSLENWTTQDAEV------------------QAVANVE---------NKSVSTSPSILAAFLK 301

  Fly   254 ISLPVVQRRTCEQQLRLYYGN---------DFELDNSL--------MCAGGEPGKDSCEGDGGSP 301
            .:.|.::.|. ||...:|.||         :|.|...|        :|........|      .|
Frog   302 ANSPALKERQ-EQVCIIYQGNPGASQLDRANFALQAQLSQNQLAPKLCFQAPDALSS------QP 359

  Fly   302 LACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVA--------NVIEWITLTTVNMPLPEERE 358
            |....|..|             |...|...  :|.:.        |.||...|....||
Frog   360 LQMHTKSPP-------------DLARPTFQ--HTEIGRNSQILYRNEIEGQGLCFREMP------ 403

  Fly   359 EVPYASPT---------------LSAGP---YLNQWNQPNYEWLPTGYPNVNSIPWQLQEANNDL 405
            ::..|||:               .||.|   .::.:::|::              ::..|.||
Frog   404 QMQMASPSPILMNVKPVYQINIENSAQPKPRTMDMYSEPSH--------------FRAPEINN-- 452

  Fly   406 ANSQYVRYYPVENVGINIHSAGHGNDQQIVRPIQQDIPKDSDDLFNSVFSTTME 459
             .|:......|||  |.:|:....|||.....|..|   ||.|.....|..|.|
Frog   453 -KSRLHHLSGVEN--IQLHNIRLDNDQTDTLSIPGD---DSTDRKPFHFKITNE 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	54/265 (20%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	54/265 (20%)
gprin3	XP_017951795.1	GRIN_C	600..720	CDD:373668
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910