DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and tmprss2.15

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_031752206.1	Gene:	tmprss2.15 / 101732233	XenbaseID:	XB-GENE-22065943	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	296	Identity:	87/296 - (29%)
Similarity:	129/296 - (43%)	Gaps:	43/296 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 YRNLGCVSTAICCPKNLIIKEPRLIINEPITDPQCGF---VNSK--GVTFSFREEDTGLAQEAEV 118
            |.||.  .:|.|...|::  ..|.|        .||.   |:|:  |.|         .|...:.
Frog   233 YTNLN--YSATCASGNMV--SLRCI--------SCGLSTKVDSRIVGGT---------PASVGDW 276

  Fly   119 PWMVALLD-ARTSSYVAGGALIAPHVVITARQRT--ENMTASQLVVRAGEWDFSTKTEQLPSVDV 180
            ||.|.||. ..||.|:.||::|.||.::||....  ...|.|...|.||    |...:...|...
Frog   277 PWQVELLKLVGTSIYLCGGSIITPHWIVTAAHCVYGSTSTPSAFKVFAG----SLTIQSYYSAGY 337

  Fly   181 PIRSIVRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNF-DFSRCIFTGWGKNSFDD 244
            .:...:.||.::......:|||:.|..:|..:.::.|:|:|:....: :...|..:|||..: :.
Frog   338 TVERALVHPSYSSYTQIYDVALLKLTAALVFTTNLRPVCLPNVGMPWAEGQPCWISGWGTTA-EG 401

  Fly   245 PSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGG-EPGKDSCEGDGGSPLACAIKD 308
            .|....|...|:|::...||.|  ...||.  .:.:::||||. ..|.|:|:||.|.||  ..|.
Frog   402 GSISKNLMAASVPIISSTTCNQ--AAVYGG--AISSTMMCAGYLSGGTDTCQGDSGGPL--VTKT 460

  Fly   309 NPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            | ..:.|.|..::|..|.....|.||.||...||||
Frog   461 N-SLWWLVGDTSWGYGCARAYKPGVYGNVTVFIEWI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	71/235 (30%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	71/235 (30%)
tmprss2.15	XP_031752206.1	LDLa	93..121	CDD:238060
		SRCR_2	164..259	CDD:406055	10/37 (27%)
		Tryp_SPc	265..498	CDD:238113	75/252 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910