DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and tmprss2.12

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_031752400.1	Gene:	tmprss2.12 / 100497514	XenbaseID:	XB-GENE-22065925	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	272	Identity:	80/272 - (29%)
Similarity:	131/272 - (48%)	Gaps:	42/272 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 SKGVTFSFREEDTGLAQEAEV-------------PWMVALLDARTSSYVAGGALIAPHVVITARQ 149
            |.|:..|.:..|.||:...|.             ||.|.|....|:  :.||::||.:.::||..
Frog   239 SSGLVVSLKCIDCGLSTYGESRIVGGSSASIGDWPWQVNLQYDDTN--LCGGSVIAANWIVTAAH 301

  Fly   150 RTENMTASQLVVRAGEWDFSTKTEQLP--------SVDVPIRSIVRHPGFNLENGANNVALVFLR 206
            ..:..|:|..:.:|    |..|. ::|        |||    .|:.||.::.:..:|::||:.|:
Frog   302 CVQGDTSSPSLWKA----FIGKI-KMPSYYDSSAYSVD----RIIVHPDYSSQTNSNDIALMKLK 357

  Fly   207 RSLTSSRHINPICMPSAPKNFDFSR-CIFTGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRL 270
            .|:..|....|:|:|:....::..: |..:|||..| ...|..:|||...:|::...||.|.: :
Frog   358 TSIAFSSISRPVCLPNYGMQWEEGQPCYISGWGTTS-QKGSISSVLKYAMVPLISPTTCNQTI-M 420

  Fly   271 YYGNDFELDNSLMCAG-GEPGKDSCEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVY 334
            |.|   .:.:|::||| .:.|.|||:||.|.||  ..|.| ..:.|.|..::|..|.....|.||
Frog   421 YNG---AITSSMICAGYPKGGVDSCQGDSGGPL--VTKTN-SLWWLVGDTSWGDGCANVYRPGVY 479

  Fly   335 TNVANVIEWITL 346
            .|:...::||.|
Frog   480 GNMTVFLQWIYL 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	71/253 (28%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	71/253 (28%)
tmprss2.12	XP_031752400.1	LDLa	127..155	CDD:238060
		SRCR_2	160..255	CDD:406055	6/15 (40%)
		Tryp_SPc	261..489	CDD:238113	70/246 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910