DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31780 and klkb1

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_002934450.3	Gene:	klkb1 / 100486524	XenbaseID:	XB-GENE-985051	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	350	Identity:	86/350 - (24%)
Similarity:	139/350 - (39%)	Gaps:	78/350 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 SNEHQCVPRHMCKVKIEFRMAMTYRNL--GCVSTAICCPKNLIIKEPRLIINEPITDPQCGFVNS 98
            |.|.:|.......::.:|   .|||.:  ||......|...                     ::|
Frog   311 SGEKECQQECTNNIRCQF---FTYRPMQSGCSENKCKCHMK---------------------ISS 351

  Fly    99 KGVTFSFRE---EDTGLAQE----------------------------AEVPWMVALLDARTSSY 132
            .|:....|.   |.:|.:..                            .|.||.|::....|:||
Frog   352 NGLPTGIRHGNGEISGFSLRLCKIKSVKGCGEPIEHANRIVGGTDSVLGEWPWQVSMHLRLTASY 416

  Fly   133 ---VAGGALIAPHVVITARQRTENMTASQL-VVRAGEWDFSTKTEQLPSVDVPIRSIVRHPGFNL 193
               ..||::|:...::||..........|: ::.:|....|..|:..|..:.  ..|:.||.:..
Frog   417 KKHACGGSIISNQWIVTAAHCFAMHPLPQMWIIYSGVVKLSNITQSTPFSET--EQIIIHPHYTG 479

  Fly   194 ENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDF-SRCIFTGWGKNSFDDPSYMNVLKKISLP 257
            .....::||:.|:..::.:.|...||:|.....|.. :.|..||||... :..|..|:|:|..:|
Frog   480 AGNGTDIALLKLKTPISFNDHQKAICLPPREPTFVLPNSCWITGWGFTE-ESGSLANILQKAEVP 543

  Fly   258 VVQRRTCEQQLRLYYGN--DFELDNSLMCAGGEPGK-DSCEGDGGSPLACAIKDNPQRYELAGIV 319
            .:....|:       ||  ...:|..::|||.:.|| |||:||.|.||||.:   .:.:.|.||.
Frog   544 QISTEECQ-------GNYEQTRIDKKILCAGYKRGKIDSCKGDSGGPLACVV---DEIWYLTGIT 598

  Fly   320 NFGVDCGLPGVPAVYTNVANVIEWI 344
            ::|..|..||.|.|||.|:...:||
Frog   599 SWGEGCARPGKPGVYTRVSEFTDWI 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	69/266 (26%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	69/266 (26%)
klkb1	XP_002934450.3	APPLE	21..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	290..373	CDD:128519	15/85 (18%)
		Tryp_SPc	391..626	CDD:238113	70/245 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	132	1.000	Inparanoid score	I4490
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960