DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31780 and hgfac

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_002939269.3	Gene:	hgfac / 100485696	XenbaseID:	XB-GENE-940012	Length:	595	Species:	Xenopus tropicalis

Alignment Length:	377	Identity:	100/377 - (26%)
Similarity:	150/377 - (39%)	Gaps:	61/377 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 GQVQAQGQNAELNQSC----------GASNE----HQCVP--RHMCKVKIEFRMAMTY--RNLG- 63
            ||...:..|.::.|||          |...|    |.|:|  ..|...:|.....|.:  :.||
Frog   220 GQYVGKYCNIDVTQSCYDSDNATEYRGIKKETQSGHSCLPWNSDMLYEEIHTGQGMNFIPKGLGS 284

  Fly    64 --------------C-------VSTAICCPKNLIIKEPRLIINEPI---TDPQCGFVNSKGVTFS 104
                          |       ||...|.......|..|:|:.|..   ..|:||..:.|.|...
Frog   285 HPYCRSPDDDEIPWCYLMNDRLVSWEHCSIPKCRDKGRRVIMQEDAVVPAPPKCGKKHEKRVVAR 349

  Fly   105 FREEDTGLAQEAEVPWMVALLDARTSSYVAGGALIAP-HVVITARQRTENMTASQLVVRAGEWDF 168
            .|......|.....||:..:.   ..:|...|:||.| .||..|....::.:.|::.|..|:..|
Frog   350 GRILGGNSALPGSHPWVAGIY---IGNYFCAGSLIQPCWVVSAAHCFADSPSKSKIRVVLGQHFF 411

  Fly   169 STKTEQLPSVDVPIRSIVRHPGFNLENGANNVALVFLRR----SLTSSRHINPICMPSAPKNF-D 228
            :..|:...:.:|. |.|........:...:::.|:.|:|    ....::.:..||:|.....| |
Frog   412 NQTTDVTQTFEVE-RYIFYDKYSVFKRNEHDIVLIKLKRINNACAKKTQFVQTICLPDVSAPFAD 475

  Fly   229 FSRCIFTGWGKNSFDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAG-GEPGKD 292
            ...|...|||:...|...|...|::..:|:|....|...  ..||  .|:..::.||| .:...|
Frog   476 DHHCQIAGWGRMHEDSTEYAQNLQEAIVPLVPDNKCSSP--EIYG--AEISENMFCAGYFDCTID 536

  Fly   293 SCEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            ||:||.|.||||. ||...  .|.|||::|..||....|.|||.|:|.::||
Frog   537 SCQGDSGGPLACE-KDKIS--YLWGIVSWGEGCGNHNKPGVYTKVSNYVDWI 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	68/237 (29%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	68/237 (29%)
hgfac	XP_002939269.3	FN2	52..98	CDD:238019
		EGF_CA	109..145	CDD:238011
		FN1	147..185	CDD:238018
		KR	235..319	CDD:294073	15/83 (18%)
		Tryp_SPc	351..585	CDD:214473	69/244 (28%)
		Tryp_SPc	352..588	CDD:238113	70/245 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910