DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31780 and egflam

DIOPT Version :9

Sequence 1:	NP_723920.1	Gene:	CG31780 / 318937	FlyBaseID:	FBgn0051780	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	XP_002938236.3	Gene:	egflam / 100485123	XenbaseID:	XB-GENE-968342	Length:	1035	Species:	Xenopus tropicalis

Alignment Length:	186	Identity:	37/186 - (19%)
Similarity:	52/186 - (27%)	Gaps:	67/186 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   290 GKDSCEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPA-----VYTNVANVIEWITLTTV 349
            |..|..|.|...:...|...||.           .|..||.|:     |.::....:.|...|:.
Frog   122 GAYSWAGKGRPSMPRDISTLPQE-----------SCMAPGSPSQPQVVVVSDTEVAVSWQQNTSE 175

  Fly   350 NMPLPEEREEVPYASPTLSAGPYLNQWNQPNYEWLPTG-------------YPN---------VN 392
            ..| |.:...:.|..|.|..            .|:|..             .||         ||
Frog   176 GSP-PVQYYSMEYIRPELDG------------IWIPIRDQIQINSMVLKGLTPNTKYQFAVKAVN 227

  Fly   393 SIPWQLQEANNDLANSQYVRYYPVENVGINIHSAGHGNDQQIVRPIQQDIPKDSDD 448
            |....|..     ..|:.:|.:..|.:|...:..|:..|           ||..||
Frog   228 SFGESLLS-----HESEIIRTFSTEELGSGSYGEGYVTD-----------PKSDDD 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:214473	12/58 (21%)
CG31780	NP_723920.1	Tryp_SPc	113..344	CDD:238113	12/58 (21%)
egflam	XP_002938236.3	FN3	34..140	CDD:238020	5/17 (29%)
		FN3	149..243	CDD:238020	20/111 (18%)
		EGF_MSP1_1	372..407	CDD:403985
		LamG	417..567	CDD:238058
		EGF_CA	586..628	CDD:238011
		LamG	654..791	CDD:238058
		EGF_CA	814..846	CDD:238011
		Laminin_G_2	886..1011	CDD:396680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910