Protein Alignment NimA and DLK1

DIOPT Version :10

• Sequence 1: NP_609691.6
• Gene: NimA / 318930
• FlyBaseID: FBgn0261514
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_003827.4
• Gene: DLK1 / 8788
• HGNCID: 2907
• Length: 383
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 103/472 - (21%)
• Similarity: 150/472 - (31%)
• Gaps: 179/472 - (37%)

  Fly     4 EKLFGKLLLLLAM--------VLPLGSGQNSTLKINTNVKDIEAGVVALPSIQGP-GNICIREEP 59
            |.|...||||||.        ..|..:.||...: :.||...:      |..||| .:.|:
Human     5 EALLRVLLLLLAFGHSTYGAECFPACNPQNGFCE-DDNVCRCQ------PGWQGPLCDQCV---- 58

  Fly    60 YVEHVQVPEMQPVRVRTSSWCME----IPPRCATFKTEMREVMRVQKLNKTRTVRFCCQGYEGNL 120
                            ||..|:.    .|.:|                       .|..|::|.|
Human    59 ----------------TSPGCLHGLCGEPGQC-----------------------ICTDGWDGEL 84

  Fly   121 SD------SQATCKPICRGGCGRGSCVMPD----ICSCEEGYIGKHCTQRCDHDRWGLDCKNLCQ 175
            .|      |.|.|       ....:||..|    .|||..||.||.| |:.|    |....|...
Human    85 CDRDVRACSSAPC-------ANNRTCVSLDDGLYECSCAPGYSGKDC-QKKD----GPCVINGSP 137

  Fly   176 CQNGAACDNKSG-----LCHCIAGWTGQFCEL-------------------------PCPQGTYG 210
            ||:|..|.:..|     .|.|..|::|.|||:                         .||.|...
Human   138 CQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFID 202

  Fly   211 IMC-RKACDCDEKPCNPQTGACIQQDQPLQLNVSHVIV---ETVNST-LEKMGIIPRPTTPVPLP 270
            ..| |...:|...||. ..|.|:|..|     ||:..:   |....| ::|..:.|:..|.:|
Human   203 KTCSRPVTNCASSPCQ-NGGTCLQHTQ-----VSYECLCKPEFTGLTCVKKRALSPQQVTRLP-- 259

  Fly   271 EVIVIKQPTSNENAQHSPKIIVHQSSSDLLENLHTAAAAGVPTPEVIHVITNGITSPQEHLAGFV 335
                                    |...|...|         ||.| |.:.  :..|:..:....
Human   260 ------------------------SGYGLAYRL---------TPGV-HELP--VQQPEHRILKVS 288

  Fly   336 GGEANSSQTATADHQSGLVVTLVSIMLLLLVAIAVGSLYVYR--------RYHH-----KNAAV- 386
            ..|.|.......:.|: :..|::.::..|:|...||.:::.:        ||:|     ||..:
Human   289 MKELNKKTPLLTEGQA-ICFTILGVLTSLVVLGTVGIVFLNKCETWVSNLRYNHMLRKKKNLLLQ 352

  Fly   387 YNANGTVTTLPANPEVV 403
            ||:...:......||.:
Human   353 YNSGEDLAVNIIFPEKI 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_609691.6	EMI	51..118	CDD:462204	8/70 (11%)
DLK1	NP_003827.4	EGF_CA	88..125	CDD:238011	14/44 (32%)
		EGF_CA	135..168	CDD:238011	10/32 (31%)
		EGF_CA	175..205	CDD:238011	3/29 (10%)
		EGF_CA	212..245	CDD:238011	11/38 (29%)