Protein Alignment NimA and SCARF1

DIOPT Version :9

• Sequence 1: NP_001285918.1
• Gene: NimA / 318930
• FlyBaseID: FBgn0261514
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_003684.2
• Gene: SCARF1 / 8578
• HGNCID: 16820
• Length: 830
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 115/557 - (20%)
• Similarity: 162/557 - (29%)
• Gaps: 232/557 - (41%)

  Fly   112 CCQGYEGNLSDSQATCKPICRG--GCGRGS-CVMPDICSCEEGYIGKHCTQRCDHDRWGLDCKNL 173
            ||.|:  ...|.:.|. |||.|  .|.:.. ||.|.:|.|:.|:.|.||:.||....||.||:..
Human    41 CCAGW--RQKDQECTI-PICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRES 102

  Fly   174 CQCQ--------NGAA----------------------CDNKSGLCHCIAGW------------- 195
            |.|.        .||.                      ||..:|:|||..||
Human   103 CPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNT 167

  Fly   196 ----------------------------------------------------------------- 195
                                                                             
Human   168 AAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSA 232

  Fly   196 -----------TGQFCELPCPQGTYGIMCRKACD-C-DEKPCNPQTGAC---------IQQDQPL 238
                       .|..||||||.|::|:.|..:|. | ..:||:|.||:|         .|..||
Human   233 ASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQP- 296

  Fly   239 QLNVSHVIVETVNSTLEK-------------------------MGIIPRPTTPVPLPEVIVIKQP 278
                  .:..|...:.|:                         :|  ||...|.|        ..
Human   297 ------CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLG--PRCEDPCP--------TG 345

  Fly   279 TSNENAQHSPKIIVHQSSSDLLENLHTAAAAGVPT-----PEVIHVITNGITSPQEHLAGFVGGE 338
            |..|:...:....|..|...:..:...:|....|:     |...|  .|..:.|.|...|.....
Human   346 TFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFH--GNNCSVPCECPEGLCHPV 408

  Fly   339 ANSSQTATADHQSGLVV-TLVSIMLLLL-VAIAVGSLYVYR-----RYHHKNAAVYNAN----GT 392
            :.|.|..:....:.|:. :||.::||.| :|......:..|     |.....|.|....    ||
Human   409 SGSCQPGSGSRDTALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKLQVWGT 473

  Fly   393 VT----TLPA----------------NPEVVLTEAAVLGKNFHEPLPEPPVAFAVTPQSNEAQPE 437
            :|    |||.                :|||          .|:....|||.|...|..|..:.||
Human   474 LTSLGSTLPCRSLSSHKLPWVTVSHHDPEV----------PFNHSFIEPPSAGWATDDSFSSDPE 528

  Fly   438 LYDSPSNNSSIKTPPYAYARKESLYSVVSPKSRKGSL 474
                  :..:.:.|.|....:|.:..|....|.:.||
Human   529 ------SGEADEVPAYCVPPQEGMVPVAQAGSSEASL 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_001285918.1	EMI	52..116	CDD:284877	2/3 (67%)
		EGF_2	170..200	CDD:285248	14/148 (9%)
SCARF1	NP_003684.2	CSRNP_N	<100..135	CDD:292638	4/34 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	516..539		5/28 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	581..688
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	715..830

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900