DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimA and Egfem1

DIOPT Version :9

Sequence 1:	NP_001285918.1	Gene:	NimA / 318930	FlyBaseID:	FBgn0261514	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	XP_006535622.1	Gene:	Egfem1 / 75740	MGIID:	1922990	Length:	658	Species:	Mus musculus

Alignment Length:	164	Identity:	46/164 - (28%)
Similarity:	62/164 - (37%)	Gaps:	52/164 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 CCQGYEGNLSDSQATCKPICRGG-C--GRGSCVMPD-----ICS----------------CEEGY 152
            |..|..|  .|...:|:....|| |  |:..|:.|.     ||:                |.:|:
Mouse   508 CLDGTFG--LDCSLSCEDCMNGGRCQEGKSGCLCPAEWTGLICNESSVLRTGEDQQAPAGCLKGF 570

  Fly   153 IGKHCTQRCDHDRWGLDCKNLCQCQNGAACDNKSGLCHCIAGWTGQFCELPCPQGTYGIMCRKAC 217
            .||             :||..|.|.|...|....|.|.|..|..|:||.|.||:|.||..|...|
Mouse   571 FGK-------------NCKRKCHCANNVHCHRVYGACMCDLGRYGRFCHLSCPRGAYGASCSLEC 622

  Fly   218 DCDEK---PCNPQTGAC----------IQQDQPL 238
            .|.|:   .|:.:.|:|          .|::.||
Mouse   623 QCVEENTLECSAKNGSCTCKSGYQGNRCQEELPL 656

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_001285918.1	EMI	52..116	CDD:284877	1/3 (33%)
NimA	NP_001285918.1	EGF_2	170..200	CDD:285248	11/29 (38%)
Egfem1	XP_006535622.1	EMI	71..140	CDD:369419
		FXa_inhibition	190..225	CDD:373209
		vWFA	<213..265	CDD:381780
		vWFA	<268..310	CDD:381780
		vWFA	<308..350	CDD:381780
		FXa_inhibition	363..398	CDD:373209
		vWFA	<395..436	CDD:381780
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900