DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimA and pear1

DIOPT Version :9

Sequence 1:	NP_001285918.1	Gene:	NimA / 318930	FlyBaseID:	FBgn0261514	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	XP_700533.4	Gene:	pear1 / 571812	ZFINID:	ZDB-GENE-091230-1	Length:	1020	Species:	Danio rerio

Alignment Length:	190	Identity:	69/190 - (36%)
Similarity:	93/190 - (48%)	Gaps:	19/190 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 NICIREEPYVEHVQVPEMQPVRVRTSSWCMEIPP----RCA----TFKTEMREVMRVQKLNKTRT 108
            |:|...|.:...|:....||....:...|.|  |    :|.    |:||..|:|:::....:.:
Zfish    29 NVCSLWESFTTSVKESYAQPFDQMSEEPCSE--PWSANKCTRHRITYKTLYRQVVKMDYRRRYQ- 90

  Fly   109 VRFCCQGYEGNLSDSQATCKPICRGGCGRGSCVMPDICSCEEGYIGKHCTQRCDHDRWGLDCKNL 173
               ||.|:    .:|:..|.|.|...|..|.||.||.|.||.|:.|..|:..||...||..|:.|
Zfish    91 ---CCPGF----YESRNKCVPRCTKECVHGRCVAPDRCQCEMGWRGDDCSSSCDGQHWGPGCRRL 148

  Fly   174 CQCQNGAACDNKSGLCHCIAGWTGQFCELPCPQGTYGIMCRKACDCDEKP-CNPQTGACI 232
            |:||||..||..:|.|.|.||:|||.|..|||...:|..||:.|.|.... ||..||.|:
Zfish   149 CECQNGGECDVLTGNCQCPAGYTGQHCHDPCPVKWFGQGCRQECQCGTGGICNQTTGECV 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_001285918.1	EMI	52..116	CDD:284877	17/71 (24%)
NimA	NP_001285918.1	EGF_2	170..200	CDD:285248	17/29 (59%)
pear1	XP_700533.4	EMI	29..96	CDD:284877	18/76 (24%)
pear1	XP_700533.4	Laminin_EGF	411..451	CDD:278482
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561378at2759
OrthoFinder	1	1.000	-	-		FOG0001631
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820