DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimA and megf6a

DIOPT Version :9

Sequence 1:	NP_001285918.1	Gene:	NimA / 318930	FlyBaseID:	FBgn0261514	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	XP_017209228.2	Gene:	megf6a / 565108	ZFINID:	ZDB-GENE-090312-12	Length:	1513	Species:	Danio rerio

Alignment Length:	172	Identity:	57/172 - (33%)
Similarity:	78/172 - (45%)	Gaps:	52/172 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 CCQGYEGNLSDS----------------------------QATCK-----PICRGGC--GR---- 137
            |..|:.|||..:                            ...||     |.|...|  ||
Zfish   754 CSPGFMGNLCQNVCPDGHFGLSCLLRCSCQNEGKCHHVTGLCVCKDGWMGPNCAKACVAGRWGPN 818

  Fly   138 -----------GSC-VMPDICSCEEGYIGKHCTQRCDHDRWGLDCKNLCQCQNGAACDNKSGLCH 190
                       ||| .:..:|.||.||:|..|.|:|....:|..|::.|||:|||.|::.||.|.
Zfish   819 CANQCDCRSSVGSCDPVIGLCHCEAGYMGPRCDQKCPQGFFGQSCQHRCQCENGAVCEHVSGACT 883

  Fly   191 CIAGWTGQFCELPCPQGTYGIMCRKACDC-DEKPCNPQTGAC 231
            |:|||||.:||.|||:|.:|:.|::.|.| :...|:|.||.|
Zfish   884 CLAGWTGTYCEKPCPEGFHGLECQQKCQCLNGGRCHPVTGGC 925

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_001285918.1	EMI	52..116	CDD:284877	1/3 (33%)
NimA	NP_001285918.1	EGF_2	170..200	CDD:285248	17/29 (59%)
megf6a	XP_017209228.2	EMI	31..100	CDD:311482
		FXa_inhibition	115..150	CDD:317114
		FXa_inhibition	156..192	CDD:317114
		FXa_inhibition	198..233	CDD:317114
		vWFA	<233..272	CDD:320736
		FXa_inhibition	285..320	CDD:317114
		vWFA	<312..358	CDD:320736
		FXa_inhibition	367..402	CDD:317114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000