DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimA and megf11

DIOPT Version :9

Sequence 1:	NP_001285918.1	Gene:	NimA / 318930	FlyBaseID:	FBgn0261514	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	XP_009291879.1	Gene:	megf11 / 563468	ZFINID:	ZDB-GENE-060503-252	Length:	1114	Species:	Danio rerio

Alignment Length:	216	Identity:	71/216 - (32%)
Similarity:	96/216 - (44%)	Gaps:	28/216 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 IEAGVVALPSIQGPG-------------NICIREEPYVEHVQVPEMQPVRVRTSSWCMEIPP--R 86
            :.|..:|||.:...|             |:|...|.|...||.....|......:.|.:|..  :
Zfish     4 VRAYPLALPVLAVLGLIISAWSLNPDDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNWFK 68

  Fly    87 CATFKTEMREVMR--VQKLNKTRTVRFCCQGY--EGNLSDSQATCKPICRGGCGRGSCVMPDICS 147
            |...:|..:...|  |:.:.:.|:.  ||.||  .|:|      |.|.|...|..|.||.||.|.
Zfish    69 CTRHRTSYKTAYRRGVRTMYRRRSQ--CCPGYFESGDL------CVPRCSEECAHGRCVSPDTCQ 125

  Fly   148 CEEGYIGKHCTQRCDHDRWGLDCKNLCQCQNGAACDNKSGLCHCIAGWTGQFCELPCPQGTYGIM 212
            ||.|:.|..|:..|:...||..|.|.|||:|||.|:..:|.|.|..|:.|..||..|..|.||..
Zfish   126 CEPGWGGLDCSSGCESGYWGPHCSNRCQCKNGALCNPITGACVCTDGYQGWRCEDLCEPGYYGKG 190

  Fly   213 CRKACDC-DEKPCNPQTGACI 232
            |:..|.| :...|:.:||.||
Zfish   191 CQLQCQCLNGATCHHETGECI 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_001285918.1	EMI	52..116	CDD:284877	16/67 (24%)
NimA	NP_001285918.1	EGF_2	170..200	CDD:285248	14/29 (48%)
megf11	XP_009291879.1	EMI	32..98	CDD:311482	16/67 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561378at2759
OrthoFinder	1	1.000	-	-		FOG0001631
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820