DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NimA and Ccbe1

DIOPT Version :9

Sequence 1:	NP_001285918.1	Gene:	NimA / 318930	FlyBaseID:	FBgn0261514	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	NP_848908.1	Gene:	Ccbe1 / 320924	MGIID:	2445053	Length:	408	Species:	Mus musculus

Alignment Length:	217	Identity:	51/217 - (23%)
Similarity:	73/217 - (33%)	Gaps:	70/217 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 TFKTEM----REVMRVQKLNKTR----------TVRF---CCQGYEGNLSD---------SQATC 127
            |::.|.    |||....|:..|:          |..|   ||:||:..|..         :||.|
Mouse    35 TYREEPEDRDREVCSENKITTTKYPCLKSSGELTTCFRKKCCKGYKFVLGQCIPEDYDICAQAPC 99

  Fly   128 KPICRGGCGRGSCVMPDICSCEEGYIGKHCTQRCDHDR-------WGLDCKNLCQCQNGAACD-- 183
            :..|....||      .:|:|..||       |.|.:|       :.||... |...|...|.
Mouse   100 EQQCTDNFGR------VLCTCYPGY-------RYDRERHQKRERPYCLDIDE-CATSNTTLCAHI 150

  Fly   184 --NKSGL--CHCIAGW----TGQFCELPCPQGTYGIMCRKACDCDEKPCNP-QTGACIQQDQPLQ 239
              |..|.  |.|..|:    .|:.|       |.|.........:||..|. :.|.|....:...
Mouse   151 CINTMGSYHCECREGYILEDDGRTC-------TRGDKYPNDTGHEEKSENEVKAGTCCATCKEFS 208

  Fly   240 LNVSHVIVETVNSTLEKMGIIP 261
                 .:.:||....:||.::|
Mouse   209 -----QMKQTVLQLKQKMALLP 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_001285918.1	EMI	52..116	CDD:284877	11/43 (26%)
NimA	NP_001285918.1	EGF_2	170..200	CDD:285248	9/39 (23%)
Ccbe1	NP_848908.1	EGF_CA	135..176	CDD:214542	11/48 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	246..335
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	361..408
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900