DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimA and Megf10

DIOPT Version :9

Sequence 1:	NP_001285918.1	Gene:	NimA / 318930	FlyBaseID:	FBgn0261514	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	NP_001094127.1	Gene:	Megf10 / 291445	RGDID:	735084	Length:	1145	Species:	Rattus norvegicus

Alignment Length:	189	Identity:	65/189 - (34%)
Similarity:	89/189 - (47%)	Gaps:	8/189 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 SIQGPGNICIREEPYVEHVQVPEMQPVRVRTSSWCMEIPP--RCATFKTEMREVMRVQKLNKTRT 108
            :::.| |:|...|.|...||.....|......:.|.:|..  :|...:...|...|..:....|.
  Rat    27 NLEDP-NVCSHWESYSVTVQESYPHPFDQIYYTSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRR 90

  Fly   109 VRFCCQGYEGNLSDSQATCKPICRGGCGRGSCVMPDICSCEEGYIGKHCTQRCDHDRWGLDCKNL 173
            ...||.|:    .:|:..|.|.|...|..|.|:.|:.|.||.|:.|.:|:..||.|.||..|.:.
  Rat    91 KSQCCPGF----YESRDVCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCSSR 151

  Fly   174 CQCQNGAACDNKSGLCHCIAGWTGQFCELPCPQGTYGIMCRKACDCDE-KPCNPQTGAC 231
            |||:|.|.|:..:|.|||.||:.|..||..|.|||||..|.:.|.|.. ..|:..||.|
  Rat   152 CQCKNRALCNPITGACHCAAGYRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHITGEC 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_001285918.1	EMI	52..116	CDD:284877	15/65 (23%)
NimA	NP_001285918.1	EGF_2	170..200	CDD:285248	14/29 (48%)
Megf10	NP_001094127.1	EMI	32..99	CDD:400092	16/70 (23%)
		EGF_Lam	281..318	CDD:214543
		EGF_CA	542..587	CDD:419698
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561378at2759
OrthoFinder	1	1.000	-	-		FOG0001631
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820