DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimA and Scarf2

DIOPT Version :9

Sequence 1:	NP_001285918.1	Gene:	NimA / 318930	FlyBaseID:	FBgn0261514	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	XP_038944006.1	Gene:	Scarf2 / 287949	RGDID:	1306013	Length:	838	Species:	Rattus norvegicus

Alignment Length:	441	Identity:	105/441 - (23%)
Similarity:	153/441 - (34%)	Gaps:	126/441 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 CMEIPPRCATFKTEMREVMRVQKLNKTRTVRFCCQGYEGNLSDSQATCKPICRGG--CGR--GSC 140
            |..:..||.|.:...         |.|:..:.|..|:.|.....:  |.| ||.|  |..  |.|
  Rat   287 CTVVEGRCLTCEPGW---------NGTKCDQPCATGFYGEGCGHR--CPP-CRDGHACNHVTGKC 339

  Fly   141 VMPDICSCEEGYIGKHCTQRCDHDRWGLDCKNLCQCQNGAACDNKSGLCHCIAGWTGQFCELPCP 205
            .     .|..|:||..|..:|.:..:|.||..:|.......||.:||.|.|..|..|..|.:.||
  Rat   340 T-----HCNAGWIGDRCETKCSNGTYGEDCAFVCSDCGSGHCDFQSGRCLCSPGVHGPHCNVTCP 399

  Fly   206 QGTYGIMCRKACDCDEKPCNPQTGACIQQDQPLQ--LNVSHVIVETVNSTLEKMGII-------- 260
            .|.:|:.|.:||.|.|:.|:|.||||..:....:  :....::...:...|..:|..
  Rat   400 AGLHGVDCAQACSCHEESCDPVTGACHLETNQRKGVMGAGALLTLLLGLLLSLLGCCCACRGKDS 464

  Fly   261 ---PRPTTPVPL-----PE-------VIVIKQPTSNENAQHSPKIIV-HQSSSDLLENLHTAAAA 309
               |||...:.|     |:       .|.:|.|......|..||::| |....:.|........:
  Rat   465 ARRPRPRRELTLGRKKAPQRFCGSFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPS 529

  Fly   310 GVPTPEVIHVITNGITSPQEHLAGFVGGEANSSQTATADHQSGLVVTLVSIMLLLLVAIAVGSLY 374
            |:..|           ||.      ....|:.|...|.|.                     |.:|
  Rat   530 GLEQP-----------SPS------WSSRASFSSFDTTDE---------------------GPVY 556

  Fly   375 VYRRYHHKNAAVYN----ANGTVTTLPANPEVVLTEAAVLGKNFHEPLPEPPVAFAVTPQSNEAQ 435
            .   ..|:.|...|    |:.::|.:||   |.|.                |:..:|......|.
  Rat   557 C---VPHEEATAENRDPEASASLTEVPA---VSLA----------------PMGTSVPGDEAAAL 599

  Fly   436 PELYDSPSNNSSIKTPP---YA-YARKES-----------LYSVVSPKSRK 471
            |...||..:.||::.|.   || .||:|:           |....||:.||
  Rat   600 PASSDSERSASSVEGPGGALYARVARREARPARTRCEAGGLSLSPSPERRK 650

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_001285918.1	EMI	52..116	CDD:284877	7/35 (20%)
NimA	NP_001285918.1	EGF_2	170..200	CDD:285248	10/29 (34%)
Scarf2	XP_038944006.1	exchanger_TraA	<74..431	CDD:411343	51/160 (32%)
Scarf2	XP_038944006.1	PHA03247	<683..837	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900