Protein Alignment NimA and DKK3

DIOPT Version :9

• Sequence 1: NP_001285918.1
• Gene: NimA / 318930
• FlyBaseID: FBgn0261514
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_001317149.1
• Gene: DKK3 / 27122
• HGNCID: 2893
• Length: 364
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 82/422 - (19%)
• Similarity: 120/422 - (28%)
• Gaps: 161/422 - (38%)

  Fly    10 LLLLLAMVLPLGSGQNSTLKINTNVKDIEAGVVALPSIQGPGNICIREEPYVEHVQVPEMQPVRV 74
            |.||||..:|.......|.        ..|.|...|::..|.......|.:.|..::.|....::
Human     9 LCLLLAAAVPTAPAPAPTA--------TSAPVKPGPALSYPQEEATLNEMFREVEELMEDTQHKL 65

  Fly    75 RTSSWCMEIPPRCATFKTEM---------------------------REVMRVQKLNKT------ 106
            |::...||.....|...:|:                           ||:.::.. |:|
Human    66 RSAVEEMEAEEAAAKASSEVNLANLPPSYHNETNTDTKVGNNTIHVHREIHKITN-NQTGQMVFS 129

  Fly   107 RTVRFCCQGYEGNLSDS------------------QATCKPICRGGCGRGSCVMPDICSCEEGYI 153
            .||.......||..|..                  |.||:| |||  .|..|.....|..::..:
Human   130 ETVITSVGDEEGRRSHECIIDEDCGPSMYCQFASFQYTCQP-CRG--QRMLCTRDSECCGDQLCV 191

  Fly   154 GKHCTQRCDHDRWGLDCKNLCQCQNGAACDNKSG--------------LCHCIAG-------W-- 195
            ..|||:.......|..|.|...||.|..|..:.|              |||..|.       |
Human   192 WGHCTKMATRGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPASRLLDLITWEL 256

  Fly   196 --TGQFCELPCPQGTYGIMCRKACDCDEKPCNPQTGACIQQDQPLQLNVSHVIVETVNSTLEKMG 258
              .|.....||..   |::|                      ||.:|           ..||. |
Human   257 EPDGALDRCPCAS---GLLC----------------------QPHRL-----------PRLEP-G 284

  Fly   259 IIPRPTTPVPLPEVIVIKQPTSNENAQHSPKII-----------------VHQSSSDLLENLHTA 306
            .:|    .:|...::.:.:||...:.....:|:                 |.|...||..:|
Human   285 FVP----SLPSHSLVYVCKPTFVGSRDQDGEILLPREVPDEYEVGSFMEEVRQELEDLERSL--- 342

  Fly   307 AAAGVPTPEVIHVITNGITSPQEHLAGFVGGE 338
                  |.|:      .:..|....|..:|||
Human   343 ------TEEM------ALREPAAAAAALLGGE 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_001285918.1	EMI	52..116	CDD:284877	14/96 (15%)
		EGF_2	170..200	CDD:285248	13/54 (24%)
DKK3	NP_001317149.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900