DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimA and Megf11

DIOPT Version :9

Sequence 1:	NP_001285918.1	Gene:	NimA / 318930	FlyBaseID:	FBgn0261514	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	XP_006511049.1	Gene:	Megf11 / 214058	MGIID:	1920951	Length:	1138	Species:	Mus musculus

Alignment Length:	188	Identity:	68/188 - (36%)
Similarity:	90/188 - (47%)	Gaps:	15/188 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 NICIREEPYVEHVQVPEMQPVRVRTSSWCMEIPP--RCA----TFKTEMREVMRVQKLNKTRTVR 110
            |:|...|.|...||.....|......:.|.:|..  :|.    ::||..|..:|.....:::
Mouse    25 NVCSHWESYAVTVQESYAHPFDQIYYTRCADILNWFKCTRHRISYKTAYRRGLRTMYRRRSQ--- 86

  Fly   111 FCCQGYEGNLSDSQATCKPICRGGCGRGSCVMPDICSCEEGYIGKHCTQRCDHDRWGLDCKNLCQ 175
             ||.||..| .|   .|.|:|...|..|.||.||.|.||.|:.|..|:..||.:.||..|.|.||
Mouse    87 -CCPGYYEN-GD---FCIPLCTEECMHGRCVSPDTCHCEPGWGGPDCSSGCDSEHWGPHCSNRCQ 146

  Fly   176 CQNGAACDNKSGLCHCIAGWTGQFCELPCPQGTYGIMCRKACDCDE-KPCNPQTGACI 232
            |||||.|:..:|.|.|..|:.|..||..|..||:|..|:..|.|.. ..|:|:||.|:
Mouse   147 CQNGALCNPITGACVCAPGFRGWRCEELCAPGTHGKGCQLLCQCHHGASCDPRTGECL 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_001285918.1	EMI	52..116	CDD:284877	16/69 (23%)
NimA	NP_001285918.1	EGF_2	170..200	CDD:285248	15/29 (52%)
Megf11	XP_006511049.1	EMI	25..92	CDD:400092	17/70 (24%)
		EGF_CA	188..233	CDD:419698	7/17 (41%)
		EGF_CA	274..319	CDD:419698
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561378at2759
OrthoFinder	1	1.000	-	-		FOG0001631
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910