DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimA and pqn-25

DIOPT Version :9

Sequence 1:	NP_001285918.1	Gene:	NimA / 318930	FlyBaseID:	FBgn0261514	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	NP_741140.1	Gene:	pqn-25 / 175759	WormBaseID:	WBGene00004114	Length:	672	Species:	Caenorhabditis elegans

Alignment Length:	172	Identity:	44/172 - (25%)
Similarity:	60/172 - (34%)	Gaps:	46/172 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 CCQGYEGNLSDSQATCKPICRGGCGRGSCVMPDICSCEEGY----IGKHC--TQRCDHDRWGLDC 170
            ||.....|      ||......||..|..::...|     |    ||..|  ||:|   ..|..|
Worm   143 CCPNTNSN------TCSSNGNNGCLAGQTMVNGQC-----YNSVNIGSACQSTQQC---LGGSQC 193

  Fly   171 K-NLCQCQNG-----AACDNKSGL------------CHCIAGWTGQFCELPCPQGTYGIMCRKAC 217
            : |:|||.:|     ..|...:||            |..:|. .||.|:.........:...:.|
Worm   194 QNNICQCYSGYVNVNQQCVISNGLNCQLGTVSYNSQCITLAS-PGQNCQTSSQCIDNSVCMNQMC 257

  Fly   218 DCDEK------PCNPQTGACIQQDQPLQLNVSHVIVETVNST 253
            .|:..      .|.|.|.:..||.|.| :|...|::..|..|
Worm   258 TCNNNYRLVYGYCVPITSSICQQTQTL-VNNQCVLLSIVGET 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_001285918.1	EMI	52..116	CDD:284877	2/3 (67%)
NimA	NP_001285918.1	EGF_2	170..200	CDD:285248	13/47 (28%)
pqn-25	NP_741140.1	EB	160..211	CDD:279949	17/58 (29%)
		EB	219..270	CDD:279949	7/51 (14%)
		EB	278..329	CDD:279949	8/22 (36%)
		EB	341..>376	CDD:279949
		EB	384..435	CDD:279949
		EB	450..496	CDD:279949
		EB	504..555	CDD:279949
		EB	563..614	CDD:279949
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900