Protein Alignment NimA and Stab1

DIOPT Version :10

• Sequence 1: NP_609691.6
• Gene: NimA / 318930
• FlyBaseID: FBgn0261514
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: XP_008769275.1
• Gene: Stab1 / 100363145
• RGDID: 2324745
• Length: 2630
• Species: Rattus norvegicus
• Alignment Length: 723
• Identity: 151/723 - (20%)
• Similarity: 230/723 - (31%)
• Gaps: 268/723 - (37%)

  Fly    10 LLLLLAMVLPL-GSG--QNSTLKINTNVKDIEAGVVALPSIQGPGNICIREEPYVEHVQVPEMQP 71
            ||||..:||.| |||  :..|::                     ...|.....::.|........
  Rat     7 LLLLCILVLCLAGSGFIRGQTVR---------------------SKRCDIHTKFITHTPCTACAA 50

  Fly    72 VRVR--TSSWCMEIPPRC---ATFKTEMR-EVMRV----QKLNKTRTVRFCCQGYEGNLSDSQAT 126
            :|.|  .|.|....|.:.   ..::.::| .|:.:    |:..|....:.||.||.|      :.
  Rat    51 IRRRLCPSGWSRNFPEKILLDCRYELQLRGSVVSLSGCSQECWKDVVQKACCPGYWG------SQ 109

  Fly   127 CKPICRGG----C-GRGSCVMPD------ICSCEEGYIGKHCTQRCDHDRWGLDCKNLCQCQNGA 180
            |.. |.||    | |.|:|:  |      .|.|:|.:.|..|....|.:|:|.||:::|.|.:|
  Rat   110 CYE-CPGGPATPCSGHGTCL--DGIGGNGTCVCQENFSGSACQDCRDPNRFGPDCQSVCNCVHG- 170

  Fly   181 ACD---NKSGLCHCIAGWTGQFC--ELP------CPQGTYGIMCRKACDCDEKPCN------PQT 228
            .|.   ..:|.|.|.||:||..|  |||      |||.:       .|..:...|.      .|.
  Rat   171 VCSRGPQGNGSCQCFAGYTGPHCDQELPVCQSLRCPQNS-------QCSAEAPACKCLPGYIQQD 228

  Fly   229 GACIQQD-QPLQLNVSHVIVETVNSTLEKMGIIPRPTTPVPLPEVIVIKQPTSN--ENAQHSPKI 290
            .||:::. .|.|                     |.|.:.:....|....||..:  ||.....|:
  Rat   229 NACLREPLDPCQ---------------------PSPCSSLARCSVTPSGQPQCHCPENYHGDGKV 272

  Fly   291 IVHQS-----------------------------------SSDLLENLHTA--------AAAGVP 312
            .:.|.                                   ::|..|..|.:        :|....
  Rat   273 CLPQDPCLTNFGGCPSNSTFCLYRAPGKATCMCWPGMTSINNDASEGCHVSCKPHSCDKSATCQV 337

  Fly   313 TPEVIHVITNGITSPQEHLAGFV--GGEANSSQTATADHQSGLVVTLVSIMLLLLVAIAV----- 370
            ||:   ..|:.:....|...|:.  |...:..|.|   :|.|||      :|.|.||||:
  Rat   338 TPD---RKTSCVCKSDEVGDGYACYGHLLHEVQRA---NQIGLV------LLRLRVAIAMLEQGC 390

  Fly   371 -------GSLYVYRRYHHKNAAVYNANGTVTTL-------------------PANPEVVLT---- 405
                   |...|........:|:.::|...|..                   |:|.....|
  Rat   391 QEILTTSGPFTVLVPSMFSVSAISSSNMNATLAQQLCRQHIIPGEHILENIGPSNTRRWWTLAGQ 455

  Fly   406 EAAVLGKNF-----HEPLPEP------------PVAFAVTPQSNEAQPELYDSPSNN-SSIKTPP 452
            |..|..||.     :|..|:.            .|...||....:..|.|...|... ..|....
  Rat   456 EITVTFKNLRYSYKYEDQPQQFSIQKANYIAANGVFHTVTALRWQLPPPLPGDPKKTVGQILAST 520

  Fly   453 YAYARKESL---------------YSVVSPKS------RKGSLD-------SHLYDEIRYHQQHH 489
            .|:.|.|::               ::|.:|.:      |.|.|.       |.|.:.:|||..:|
  Rat   521 EAFTRFETILENCGLPAMLDGPGPFTVFAPSNEAVDSLRDGRLIYLFTAGLSKLQELVRYHIYNH 585

  Fly   490 HQQHHPRSHQHVQHSTTASQFL-----------------PARPQIMPANDQFSNGSVHPHQRSHH 537
            .|....:.....:..|.|:|.|                 |.|...:||    :||.:      |.
  Rat   586 GQLTVEKLISKGRFLTMANQVLTVNISEEGRILLGPEGVPVRRVDVPA----ANGVI------HM 640

  Fly   538 VTHLIIPP 545
            :..:::||
  Rat   641 LEGILLPP 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimA	NP_609691.6	EMI	51..118	CDD:462204	15/76 (20%)
Stab1	XP_008769275.1	FAS1	502..647	CDD:441906	30/154 (19%)
		EGF_3	834..863	CDD:463759
		EGF_3	918..949	CDD:463759
		EGF_3	955..991	CDD:463759
		Fasciclin	<1100..1180	CDD:396845
		Fasciclin	1224..1313	CDD:470649
		EGF_3	1519..1555	CDD:463759
		EGF_3	1561..1595	CDD:463759
		EGF_3	1604..1641	CDD:463759
		Fasciclin	1666..1770	CDD:396845
		Fasciclin	1796..1926	CDD:396845
		EGF_Lam	2037..2082	CDD:238012
		EGF_3	2154..2189	CDD:463759
		EGF_3	2195..2232	CDD:463759
		Link_Domain	2267..2359	CDD:470631
		FAS1	2426..2521	CDD:214719
		Fasciclin	391..494	CDD:470649	15/102 (15%)