Protein Alignment Prosbeta5R2 and PSMB8

DIOPT Version :9

• Sequence 1: NP_001286022.1
• Gene: Prosbeta5R2 / 318924
• FlyBaseID: FBgn0051742
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_683720.2
• Gene: PSMB8 / 5696
• HGNCID: 9545
• Length: 276
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 121/280 - (43%)
• Similarity: 169/280 - (60%)
• Gaps: 19/280 - (6%)

  Fly     1 MALESICGMDK-------LPFMKSFGYRTSKQTIEEIRVASSNMDNP-LAIMAPPYENPRESVKK 57
            |||..:||..:       ||...| |.|:.....      |.:|.:| ||:  |....|.|..:.
Human     1 MALLDVCGAPRGQRPESALPVAGS-GRRSDPGHY------SFSMRSPELAL--PRGMQPTEFFQS 56

  Fly    58 LNALSE--VQIDFDHGTTTVGFVYQGGIILCVDSRATSGKLIGSQSIHKVVQVNQYIMGTTAGGA 120
            |....|  |||:..|||||:.|.:|.|:|..|||||::|..|.:..::||:::|.|::||.:|.|
Human    57 LGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCA 121

  Fly   121 ADCTYWDRALTRECRLHELRYKERLPVQSAAKYISNVAAEYKGMGLCMGMMLAGWSPEGPSLVYV 185
            |||.||:|.|.:||||:.||..||:.|.:|:|.:||:..:|:||||.||.|:.||..:||.|.||
Human   122 ADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYV 186

  Fly   186 DSNGLRIHGKLFAVGSGAPNALGILDSDYRLDLSDNEAYDLAFLAVYHATMTDIFSGGVVRLYHM 250
            |.:|.|:.|.:|:.|||...|.|::||.||.:||..|||||...|:.:||..|.:|||||.:|||
Human   187 DEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHM 251

  Fly   251 DQGNWRNVANKDCQELHEQY 270
            .:..|..|.:.|..:|..||
Human   252 KEDGWVKVESTDVSDLLHQY 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5R2	NP_001286022.1	PTZ00488	46..279	CDD:185666	106/227 (47%)
		proteasome_beta_type_5	72..259	CDD:239730	91/186 (49%)
PSMB8	NP_683720.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33		10/32 (31%)
		proteasome_beta_type_5	73..260	CDD:239730	91/186 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53702
OrthoDB	1	1.010	-	-		D396507at33208
OrthoFinder	1	1.000	-	-		FOG0001305
OrthoInspector	1	1.000	-	-		mtm8519
orthoMCL	1	0.900	-	-		OOG6_100897
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X647
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.790