Protein Alignment Prosbeta5R2 and PSMB8

DIOPT Version :10

• Sequence 1: NP_724081.1
• Gene: Prosbeta5R2 / 318924
• FlyBaseID: FBgn0051742
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_683720.2
• Gene: PSMB8 / 5696
• HGNCID: 9545
• Length: 276
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 121/280 - (43%)
• Similarity: 169/280 - (60%)
• Gaps: 19/280 - (6%)

  Fly     1 MALESICGMDK-------LPFMKSFGYRTSKQTIEEIRVASSNMDNP-LAIMAPPYENPRESVKK 57
            |||..:||..:       ||...| |.|:.....      |.:|.:| ||:  |....|.|..:.
Human     1 MALLDVCGAPRGQRPESALPVAGS-GRRSDPGHY------SFSMRSPELAL--PRGMQPTEFFQS 56

  Fly    58 LNALSE--VQIDFDHGTTTVGFVYQGGIILCVDSRATSGKLIGSQSIHKVVQVNQYIMGTTAGGA 120
            |....|  |||:..|||||:.|.:|.|:|..|||||::|..|.:..::||:::|.|::||.:|.|
Human    57 LGGDGERNVQIEMAHGTTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCA 121

  Fly   121 ADCTYWDRALTRECRLHELRYKERLPVQSAAKYISNVAAEYKGMGLCMGMMLAGWSPEGPSLVYV 185
            |||.||:|.|.:||||:.||..||:.|.:|:|.:||:..:|:||||.||.|:.||..:||.|.||
Human   122 ADCQYWERLLAKECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYV 186

  Fly   186 DSNGLRIHGKLFAVGSGAPNALGILDSDYRLDLSDNEAYDLAFLAVYHATMTDIFSGGVVRLYHM 250
            |.:|.|:.|.:|:.|||...|.|::||.||.:||..|||||...|:.:||..|.:|||||.:|||
Human   187 DEHGTRLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHM 251

  Fly   251 DQGNWRNVANKDCQELHEQY 270
            .:..|..|.:.|..:|..||
Human   252 KEDGWVKVESTDVSDLLHQY 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5R2	NP_724081.1	proteasome_beta_type_5	72..259	CDD:239730	91/186 (49%)
PSMB8	NP_683720.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33		10/32 (31%)
		proteasome_beta_type_5	73..260	CDD:239730	91/186 (49%)