DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta5R2 and PSMB7

DIOPT Version :9

Sequence 1:	NP_001286022.1	Gene:	Prosbeta5R2 / 318924	FlyBaseID:	FBgn0051742	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_002790.1	Gene:	PSMB7 / 5695	HGNCID:	9544	Length:	277	Species:	Homo sapiens

Alignment Length:	226	Identity:	63/226 - (27%)
Similarity:	103/226 - (45%)	Gaps:	30/226 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LAIMAPP-----YENPRESVKKLNALSEVQIDF-----------DHGTTTVGFVYQGGIILCVDS 89
            :::.|||     ::|.|.     ||:.|.  ||           ..|||..|.||:.||:|..|:
Human     4 VSVYAPPVGGFSFDNCRR-----NAVLEA--DFAKRGYKLPKVRKTGTTIAGVVYKDGIVLGADT 61

  Fly    90 RATSGKLIGSQSIHKV--VQVNQYIMGTTAGGAADCTYWDRALTRECRLHELRYKERLP-VQSAA 151
            |||.|.::..::..|:  :..|.|..|  ||.|||.....:.::....||.|. ..||| |.:|.
Human    62 RATEGMVVADKNCSKIHFISPNIYCCG--AGTAADTDMTTQLISSNLELHSLS-TGRLPRVVTAN 123

  Fly   152 KYISNVAAEYKGMGLCMGMMLAGWSPEGPSLVYVDSNGLRIHGKLFAVGSGAPNALGILDSDYRL 216
            :.:..:...|:|. :...::|.|....||.|..:..:|.........:|||:..|:.:.:..:|.
Human   124 RMLKQMLFRYQGY-IGAALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRP 187

  Fly   217 DLSDNEAYDLAFLAVYHATMTDIFSGGVVRL 247
            |:.:.||.:|...|:......|:.||..:.|
Human   188 DMEEEEAKNLVSEAIAAGIFNDLGSGSNIDL 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5R2	NP_001286022.1	PTZ00488	46..279	CDD:185666	62/221 (28%)
Prosbeta5R2	NP_001286022.1	proteasome_beta_type_5	72..259	CDD:239730	52/179 (29%)
PSMB7	NP_002790.1	proteasome_beta_type_7	44..232	CDD:239732	52/179 (29%)
PSMB7	NP_002790.1	Pr_beta_C	236..271	CDD:403609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810