Protein Alignment Prosbeta5R2 and PSMA6

DIOPT Version :10

• Sequence 1: NP_724081.1
• Gene: Prosbeta5R2 / 318924
• FlyBaseID: FBgn0051742
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_002782.1
• Gene: PSMA6 / 5687
• HGNCID: 9535
• Length: 246
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 44/224 - (19%)
• Similarity: 79/224 - (35%)
• Gaps: 43/224 - (19%)

  Fly    31 RVASSNMDNPLAIMAPPYENPRESVKKLNALSEVQIDFDHGTTTVGFVYQGGI----------IL 85
            |.:|:..|..:.|.:|.           ..|.:|:..|.       .:.|||:          .:
Human     3 RGSSAGFDRHITIFSPE-----------GRLYQVEYAFK-------AINQGGLTSVAVRGKDCAV 49

  Fly    86 CVDSRATSGKLIGSQSIHKVVQVNQYIMGTTAGGAADCTYWDRALTRECRLHELRYKERLPVQSA 150
            .|..:....||:.|.::..:.::.:.|.....|..||.....:....|....:.:|...:||...
Human    50 IVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDML 114

  Fly   151 AKYISNVA------AEYKGMGLCMGMMLAGWSPE-GPSLVYVDSNGLRIHGKLFAVGSGAPNALG 208
            .|.|::::      ||.:.:|.|  |:|.|...| ||.:...|..|.....|..|.|.....:..
Human   115 CKRIADISQVYTQNAEMRPLGCC--MILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTS 177

  Fly   209 ILDSDYRLDLSDNEAYDLAFLAVYHATMT 237
            .|:...:      :.:|..|.......:|
Human   178 FLEKKVK------KKFDWTFEQTVETAIT 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5R2	NP_724081.1	proteasome_beta_type_5	72..259	CDD:239730	36/183 (20%)
PSMA6	NP_002782.1	proteasome_alpha_type_6	8..220	CDD:239723	42/219 (19%)