Protein Alignment Prosbeta5R2 and PSMA4

DIOPT Version :10

• Sequence 1: NP_724081.1
• Gene: Prosbeta5R2 / 318924
• FlyBaseID: FBgn0051742
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_002780.1
• Gene: PSMA4 / 5685
• HGNCID: 9533
• Length: 261
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 53/237 - (22%)
• Similarity: 97/237 - (40%)
• Gaps: 61/237 - (25%)

  Fly    70 HGTTTVGFVYQGGIILCVDSRATSGKLIGSQSIH----------KVVQVNQYIMGTTAGGAADCT 124
            |..|.:|.:...|::|..:.|          :||          |:.::|:.:..:.||..:|.
Human    30 HAGTCLGILANDGVLLAAERR----------NIHKLLDEVFFSEKIYKLNEDMACSVAGITSDA- 83

  Fly   125 YWDRALTRECRL----HELRYKERLPVQSAAKYISNVAAEYKGMGLCMGMMLAGWSPEGPSLVYV 185
               ..||.|.||    :.|:|:|.:|.:.....:.::...|...|        |..|.|.||:|:
Human    84 ---NVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFG--------GKRPFGVSLLYI 137

  Fly   186 -------------DSNGLRIHGKLFAVGSGAPNALGILDSDYRL-DLSDNEAYDLAFLAVYHATM 236
                         |.:|.....|...:|:.:..|:.:|..||:. :::...|..|| :.|.:.||
Human   138 GWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALA-IKVLNKTM 201

  Fly   237 TDI--FSGGVVRLYHMDQGNWRNV----ANKDCQEL---HEQ 269
             |:  .|...|.:..:.:.|.:.|    ..|:.::|   ||:
Human   202 -DVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEE 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5R2	NP_724081.1	proteasome_beta_type_5	72..259	CDD:239730	48/220 (22%)
PSMA4	NP_002780.1	proteasome_alpha_type_4	3..216	CDD:239721	47/209 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..261		2/3 (67%)