DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta5R2 and Prosbeta2R1

DIOPT Version :9

Sequence 1:	NP_001286022.1	Gene:	Prosbeta5R2 / 318924	FlyBaseID:	FBgn0051742	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_572267.1	Gene:	Prosbeta2R1 / 31511	FlyBaseID:	FBgn0029812	Length:	307	Species:	Drosophila melanogaster

Alignment Length:	205	Identity:	53/205 - (25%)
Similarity:	92/205 - (44%)	Gaps:	15/205 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 IMAPPYENPRESVKKLNALSEVQIDFDHGTTTVGFVYQGGIILCVDSRATSGKLIGSQSIHKVVQ 107
            :::..||.|: ::|.             ||:.||.:|:.|:||..|:|||.|.::..::..|:..
  Fly    34 LLSKGYEPPK-AIKT-------------GTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKIHH 84

  Fly   108 VNQYIMGTTAGGAADCTYWDRALTRECRLHELRYKERLPVQSAAKYISNVAAEYKGMGLCMGMML 172
            :..:|....||.|||........:.|..||.|..:.|:||..|:..:......|:| .:...:::
  Fly    85 LQDHIYCCGAGTAADTEMITLTTSAELDLHRLNTERRVPVVCASMMLRRTLFRYQG-HIGAALVM 148

  Fly   173 AGWSPEGPSLVYVDSNGLRIHGKLFAVGSGAPNALGILDSDYRLDLSDNEAYDLAFLAVYHATMT 237
            .|....||.|..:...|........|:|||...|:.:|:..::.||...:...|...|:......
  Fly   149 GGVDTTGPQLYCIYPCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQGKQLVREAISAGVFN 213

  Fly   238 DIFSGGVVRL 247
            |:.||..:.|
  Fly   214 DLGSGSNIDL 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5R2	NP_001286022.1	PTZ00488	46..279	CDD:185666	53/202 (26%)
Prosbeta5R2	NP_001286022.1	proteasome_beta_type_5	72..259	CDD:239730	48/176 (27%)
Prosbeta2R1	NP_572267.1	20S_bact_beta	48..241	CDD:163402	49/177 (28%)
		proteasome_beta_type_7	49..236	CDD:239732	48/176 (27%)
		Pr_beta_C	241..274	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440970
Domainoid	1	1.000	44	1.000	Domainoid score	I729
eggNOG	1	0.900	-	-		E1_COG0638
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840