DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta5R2 and psmb8a

DIOPT Version :9

Sequence 1:	NP_001286022.1	Gene:	Prosbeta5R2 / 318924	FlyBaseID:	FBgn0051742	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_571467.3	Gene:	psmb8a / 30666	ZFINID:	ZDB-GENE-990415-141	Length:	271	Species:	Danio rerio

Alignment Length:	283	Identity:	116/283 - (40%)
Similarity:	169/283 - (59%)	Gaps:	30/283 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALESICGMDKLPFMKSFGYRTSKQTI-------------EEIRVASSNMDNPLAIMAPPYENPR 52
            |||..:.|. |......||:   |||:             :|..|       |:.:      :|.
Zfish     1 MALLDVSGY-KYNSASQFGF---KQTLLDRSNHYSFGTKCQEFAV-------PVGV------DPS 48

  Fly    53 ESVKKLNALSEVQIDFDHGTTTVGFVYQGGIILCVDSRATSGKLIGSQSIHKVVQVNQYIMGTTA 117
            :.:|..:....|.||.:|||||:.|.::.|:|:.|||||::||.|.|:..:||:::|.|::||.:
Zfish    49 KFLKSCSCEDGVCIDLNHGTTTLAFKFRHGVIVAVDSRASAGKYIASKEANKVIEINPYLLGTMS 113

  Fly   118 GGAADCTYWDRALTRECRLHELRYKERLPVQSAAKYISNVAAEYKGMGLCMGMMLAGWSPEGPSL 182
            |.||||.||:|.|.:||||::||.|:|:.|.:|:|.:||:...|:||||.||.|:.||..:||.|
Zfish   114 GSAADCQYWERLLAKECRLYKLRNKQRISVSAASKLLSNMMLGYRGMGLSMGSMICGWDKQGPGL 178

  Fly   183 VYVDSNGLRIHGKLFAVGSGAPNALGILDSDYRLDLSDNEAYDLAFLAVYHATMTDIFSGGVVRL 247
            .|||.||.|:.|::|:.|.|...|.|::||.||.|::..|||:|....:.|||..|.:|||||.|
Zfish   179 YYVDDNGTRLSGRMFSTGCGNSYAYGVVDSGYREDMTVEEAYELGRRGIAHATHRDAYSGGVVNL 243

  Fly   248 YHMDQGNWRNVANKDCQELHEQY 270
            |||.:..|..|..:|..||..:|
Zfish   244 YHMQEDGWIKVCKEDVSELIHRY 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5R2	NP_001286022.1	PTZ00488	46..279	CDD:185666	103/225 (46%)
Prosbeta5R2	NP_001286022.1	proteasome_beta_type_5	72..259	CDD:239730	91/186 (49%)
psmb8a	NP_571467.3	PTZ00488	37..266	CDD:185666	105/241 (44%)
psmb8a	NP_571467.3	proteasome_beta_type_5	68..255	CDD:239730	91/186 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53702
OrthoDB	1	1.010	-	-		D396507at33208
OrthoFinder	1	1.000	-	-		FOG0001305
OrthoInspector	1	1.000	-	-		mtm6525
orthoMCL	1	0.900	-	-		OOG6_100897
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X647
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.790