DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta5R2 and Psmb5

DIOPT Version :9

Sequence 1:	NP_001286022.1	Gene:	Prosbeta5R2 / 318924	FlyBaseID:	FBgn0051742	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_001099197.2	Gene:	Psmb5 / 29425	RGDID:	61879	Length:	263	Species:	Rattus norvegicus

Alignment Length:	231	Identity:	109/231 - (47%)
Similarity:	155/231 - (67%)	Gaps:	10/231 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LAIMAPPYENPRESVKKLNALSEVQIDFDHGTTTVGFVYQGGIILCVDSRATSGKLIGSQSIHKV 105
            |::.||.:..|.|.          :|:..|||||:.|.:|.|:|:..|||||:|..|.||::.||
  Rat    39 LSLAAPSWGVPEEP----------RIEMLHGTTTLAFKFQHGVIVAADSRATAGAYIASQTVKKV 93

  Fly   106 VQVNQYIMGTTAGGAADCTYWDRALTRECRLHELRYKERLPVQSAAKYISNVAAEYKGMGLCMGM 170
            :::|.|::||.|||||||::|:|.|.|:||::|||.|||:.|.:|:|.::|:..:||||||.||.
  Rat    94 IEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGT 158

  Fly   171 MLAGWSPEGPSLVYVDSNGLRIHGKLFAVGSGAPNALGILDSDYRLDLSDNEAYDLAFLAVYHAT 235
            |:.||...||.|.||||.|.||.|..|:||||:..|.|::|..|..||...||||||..|:|.||
  Rat   159 MICGWDKRGPGLYYVDSEGNRISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQAT 223

  Fly   236 MTDIFSGGVVRLYHMDQGNWRNVANKDCQELHEQYS 271
            ..|.:|||.|.|||:.:..|..|::.:..:||::|:
  Rat   224 YRDAYSGGAVNLYHVREDGWIRVSSDNVADLHDKYT 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta5R2	NP_001286022.1	PTZ00488	46..279	CDD:185666	107/226 (47%)
Prosbeta5R2	NP_001286022.1	proteasome_beta_type_5	72..259	CDD:239730	97/186 (52%)
Psmb5	NP_001099197.2	PTZ00488	29..263	CDD:185666	109/231 (47%)
Psmb5	NP_001099197.2	proteasome_beta_type_5	60..247	CDD:239730	97/186 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53702
OrthoDB	1	1.010	-	-		D396507at33208
OrthoFinder	1	1.000	-	-		FOG0001305
OrthoInspector	1	1.000	-	-		mtm8992
orthoMCL	1	0.900	-	-		OOG6_100897
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X647
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.790